CPAP to Improve Swallow Function Post Total Laryngectomy

Status Completed

Clinical Trial Summary

Investigator initiated prospective study to determine whether use of Continuous Positive Airway Pressure (CPAP) can improve the swallow function in patients who underwent total laryngectomy and are experiencing difficulty swallowing

Clinical Trial Description

Total laryngectomy is a procedure that involves surgical removal of the larynx and separation of the digestive and airway tracts. The procedure is typically conducted for cases of laryngeal cancer and intractable aspiration. Following this procedure, patients are no longer at risk for aspiration; however some patients continue to experience difficulties in propulsion of food or drink throughout the pharynx. Previous research has demonstrated a reduction in pharyngeal contractile pressure and increased pharyngeal transit time in patients post laryngectomy. Continuous Positive Airway Pressure (CPAP) may assist bolus propulsion in these patients by increasing pressure in the direction of bolus flow. This study aims to evaluate the utility of a CPAP mask to improve pharyngeal swallow outcomes during Video Fluoroscopic Swallowing Exam (VFSE) in patients with dysphagia following total laryngectomy. This specific population could be well-suited for this application, since the digestive tract and airway are completely separate and there is no risk of the aspiration into the airway. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03328702
Study type	Interventional
Source	University of California, Davis
Contact
Status	Completed
Phase	N/A
Start date	June 27, 2016
Completion date	November 8, 2022

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03284892` - Screening and Intervention of Postextubation Dysphagia	N/A
Not yet recruiting	`NCT05958173` - Effects of 6-month of Treatment With TRPV1 and TRPA1 Agonists in Older Patients With OD	N/A
Recruiting	`NCT04359199` - QUantitative Assessment of Swallowing After Radiation (QUASAR)
Terminated	`NCT03387267` - Videofluoroscopic Swallowing Study (VFSS)	N/A
Recruiting	`NCT06250426` - Effect of a Cooling Sensation Flavor on the Swallow Response in Post-stroke Patients With Oropharyngeal Dysphagia	N/A
Not yet recruiting	`NCT02874352` - Incidence of Dysphagia in Intensive Care Patients With Tracheostomy	N/A
Recruiting	`NCT05720871` - Treatment of Chronic Post-stroke Oropharyngeal Dysphagia With Paired Stimulation	N/A
Recruiting	`NCT04130867` - Rehabilitation Manometry Study
Completed	`NCT05405829` - Health Education to Caregivers to Reduce Aspiration Pneumonia	N/A
Recruiting	`NCT05421689` - Autologous Muscle Derived Cells for Treatment of Tongue Dysphagia	Phase 1/Phase 2
Recruiting	`NCT02838316` - Autologous Muscle Derived Cells for Gastro-Intestinal Repair (AMDC-GIR) for Tongue Dysphagia	Phase 1
Enrolling by invitation	`NCT05325658` - Influence of Modified Diet, Exercise and Electrical Swallowing Muscle Stimulation on Swallowing Function and Quality of Life in Elderly Patients With Oropharyngeal Dysphagia
Not yet recruiting	`NCT06368830` - Oral and Swallowing Function in Older Adults
Completed	`NCT02959450` - Design and Implementation of a Nutritional Intervention in Patients With Oropharyngeal Dysphagia	N/A
Completed	`NCT02396992` - Minimal-Massive Intervention in Elderly Patients With Dysphagia	N/A
Not yet recruiting	`NCT05862142` - A Predictive Model for Oropharyngeal Dysphagia in Non-hospitalized Older Patients
Recruiting	`NCT04581486` - Effectiveness of an Optimal-Massive Intervention in Older Patients With Dysphagia	N/A
Terminated	`NCT01971320` - Evaluation of Transcutaneous Electrical Stimulation in Post Stroke Dysphagia	Phase 3
Completed	`NCT01032928` - Respiratory-Swallow Training in Veterans With Oropharyngeal Cancer	Phase 2
Completed	`NCT02170454` - Effect of Pharyngeal Inhibition by rTMS on Swallowing Function	N/A