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Obstructive Sleep Apnea clinical trials

View clinical trials related to Obstructive Sleep Apnea.

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NCT ID: NCT04922112 Withdrawn - Clinical trials for Obstructive Sleep Apnea

Sleep Apnea in Head and Neck Cancer Patients at the University of Colorado

OSA-HN
Start date: April 20, 2021
Phase: N/A
Study type: Interventional

Obstructive sleep apnea (OSA) is increasingly recognized in patients with squamous cell carcinoma of the head and neck (SCCHN). The prevalence prior and after cancer therapy is not well understood. OSA is identified as a contributing factor for daytime somnolence and quality of life (QOL), yet treatment of OSA in the SCCHN population has not been studied. The investigators hope to identify the disease course of sleep apnea, risk factors for development, and impact on QOL with treatment of OSA in a population of patients with SCCHN.

NCT ID: NCT04473534 Withdrawn - Clinical trials for Obstructive Sleep Apnea

Web Based CBT-I in Patients With OSA and Insomnia

Start date: March 10, 2021
Phase: N/A
Study type: Interventional

Obstructive sleep apnea (OSA) and insomnia often occur in the same patient. Recent studies have demonstrated the efficacy of cognitive behavioral therapy (CBT-I) in patients with insomnia and OSA. Our aim is to verify the efficacy of web based CBT-I in patients with OSA and insomnia and the effect of web based CBT-I on the acceptance and adherence to CPAP (Continuous Positive Airway Pressure) therapy.

NCT ID: NCT04205136 Withdrawn - Clinical trials for Obstructive Sleep Apnea

Spironolactone to Improve Apnea and Cardiovascular Markers in Obstructive Sleep Apnea Patients

Start date: March 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to test whether Spironolactone can improve the severity of obstructive sleep apnea and improve cardiovascular biomarkers in people who are not regularly using their Positive Airway Pressure (PAP) therapy.

NCT ID: NCT04063436 Withdrawn - Clinical trials for Obstructive Sleep Apnea

Evaluation of a New Nasal Pillows Mask for the Treatment of Obstructive Sleep Apnea

Start date: September 23, 2019
Phase: N/A
Study type: Interventional

This clinical trial is designed to evaluate the performance, comfort, and usability of a new nasal pillows mask for the treatment of obstructive sleep apnea (OSA) in a home environment.

NCT ID: NCT04021550 Withdrawn - Clinical trials for Obstructive Sleep Apnea

Improving 24-hour Blood Pressure in Obstructive Sleep Apnea

Start date: May 2023
Phase: Early Phase 1
Study type: Interventional

This study examines the combined effects of an angiotensin receptor blocker (ARB), antioxidant supplementation, and continuous positive airway pressure (CPAP) therapy on the lowering of 24-hour blood pressure in persons with moderate to severe Obstructive Sleep Apnea (OSA). All participants will undergo CPAP therapy as prescribed by their doctor; however, half of the participants will receive the combined ARB and antioxidant treatment while the other half of the participants will receive a placebo.

NCT ID: NCT04013399 Withdrawn - Clinical trials for Obstructive Sleep Apnea

Obstructive Sleep Apnea Treatment and Insulin Sensitivity in Pregnancy

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

This study will evaluate the effect of treatment of obstructive sleep apnea on insulin sensitivity in pregnant women. Women in their third trimester of pregnancy will be randomized to receive treatment or no treatment for one month.

NCT ID: NCT04011358 Withdrawn - Clinical trials for Obstructive Sleep Apnea

Retinal Vein Occlusion and Obstructive Sleep Apnea: A Case Control Study

SASOVR
Start date: September 2021
Phase: N/A
Study type: Interventional

This study purpose is to evaluate the association between Retinal Vein Occlusion and Obstructive Sleep Apnea.

NCT ID: NCT04009486 Withdrawn - Clinical trials for Obstructive Sleep Apnea

Whole Body Vibration and the Brain in OSA

Start date: April 2020
Phase: N/A
Study type: Interventional

Participants will have an overnight polysomnography (recording apnea-hypopnea index), MRI (brain structure), and a sleep symptoms questionnaire for baseline data. Participants will then undergo 6 weeks of whole body vibration (using the whole body vibration device), 3 times a week for 30 minutes sessions. After 6 weeks, participants will have complete another polysomnography, MRI and sleep questionnaire.

NCT ID: NCT03861468 Withdrawn - Clinical trials for Obstructive Sleep Apnea

Medico-economics and QoL of Obese Patients Followed by Medical Analysis Laboratories (BIOSAOS )

BIOSAOS
Start date: September 14, 2019
Phase: N/A
Study type: Interventional

Obesity is a major risk factor for obstructive sleep apnea (OSA). However, OSA is still largely under diagnosed in patients with a high cardiovascular risk. In this population the STOP-BANG questionnaire facilitates OSA screening. Moreover, blood bicarbonate concentration is a simple tool to screen for chronic respiratory disease and if elevated, is a marker of cardiometabolic comorbidities in obese patients. A combination of blood bicarbonate concentration and STOP BANG score could provide a cost-effective method of screening for OSA in obese patients. Such screening could enable earlier management and might significantly reduce the costs of treatment and improve the quality of life of patients at 2 years.

NCT ID: NCT03613558 Withdrawn - Clinical trials for Obstructive Sleep Apnea

Dex as Analgesic Adjuvant in OSA Patients

Start date: July 2014
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to assess whether intravenous peri-operative Dexmedetomidine reduces opioid requirements and or improves pain control after Uvulopalatopharyngoplasty (UPPP) in patients with obstructive sleep apnea (OSA).