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Obstructive Sleep Apnea clinical trials

View clinical trials related to Obstructive Sleep Apnea.

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NCT ID: NCT06319612 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

Effectiveness of Stellate Ganglion Block for the Treatment of Obstructive Sleep Apnea

Start date: March 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test the efficacy of stellate ganglion block in Obstructive Sleep Apnea. The main question it aims to answer are: • Can stellate ganglion block improve Obstructive Sleep Apnea? Patients were randomly divided into two groups, all provided with routine therapy. Based on this, the experimental group was given stellate ganglion block. The video fluoroscopic swallowing study was done to test the swallowing function before and after the study.

NCT ID: NCT06319482 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

The Adherence of Proactive Sleep Apnea Therapy

Start date: April 15, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the adherence to Positive Airway Pressure (PAP) therapy for newly diagnosed Obstructive Sleep Apnea (OSA) patients. The main question(s) it aims to answer are: 1. To compare the adherence of proactive therapy and conventional Automatic-PAP (APAP) therapy short-term (3 months) and long-term (12 months) for newly diagnosed OSA patients. 2. To compare health outcomes (AHI, nightly pressure, and patient-reported outcomes) between proactive therapy and conventional APAP therapy.

NCT ID: NCT06317701 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation

Start date: March 2024
Phase:
Study type: Observational

The purpose of this study is to determine if the treatment of Obstructive sleep apnea (OSA) by hypoglossal nerve stimulation (HGNS) will alter glucose metabolism. The study team will also determine if the treatment of Obstructive sleep apnea (OSA) by (hypoglossal nerve stimulation) HGNS will alter predictors of cardiovascular outcomes.

NCT ID: NCT06314477 Not yet recruiting - Asthma Clinical Trials

Effect of CPAP Treatment in Patients With Severe Uncontrolled Asthma: The ASTHMA-SLEEP Trial

Start date: April 2024
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the impact of CPAP treatment on asthma control in patients with severe uncontrolled asthma and obstructive sleep apnea (OSA)

NCT ID: NCT06311045 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

Obstructive Sleep Apnea (OSA) and Sex-Specific Responses to N-acetylcysteine (NAC)

Start date: April 2024
Phase: N/A
Study type: Interventional

This is a randomized controlled trial (RCT) of 4 weeks of study supplement N-acetylcysteine (NAC) versus placebo in persons with significant obstructive sleep apnea (OSA) who are receiving positive airway pressure therapy (PAP), the standard of care therapy. The purpose of the study is to determine if NAC is associated with sex-specific changes in overnight oxidative stress, inflammation, as well as endothelial dysfunction in persons with OSA.

NCT ID: NCT06265792 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

Efficacy of Stellate Ganglion Block in Obstructive Sleep Apnea

OSA
Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test the efficacy of stellate ganglion block in Obstructive Sleep Apnea. The main question it aims to answer are: • Can stellate ganglion block improve Obstructive Sleep Apnea? Patients were randomly divided into two groups, all provided with routine therapy. Based on this, the experimental group was given stellate ganglion block. The video fluoroscopic swallowing study was done to test the swallowing function before and after the study.

NCT ID: NCT06261034 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

A Study of Sex Differences in Neurocirculatory Control

Start date: March 2024
Phase:
Study type: Observational

The purpose of this study is to investigate potential sex differences in neurocirculatory control of blood pressure in patients with untreated obstructive sleep apnea (OSA).

NCT ID: NCT06258837 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils

TOPS-ST
Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effectiveness of a novel personalized surgical approach to the standard AT in children with small tonsils (ST). This will be accomplished by randomizing children with ST and OSA to one of these two treatments and comparing outcomes after 6 months. It is the investigators' central hypothesis that a personalized drug-induced sleep endoscopy (DISE)-directed surgical approach that uses existing procedures to address the specific fixed and dynamic anatomic features causing obstruction (ie, anatomic endotypes) in each child with ST will perform better than the currently recommended standard first line approach of AT. This novel approach may improve OSA outcomes and reduce the burden of unnecessary AT or secondary surgery for persistent OSA after an ineffective AT. To test this hypothesis, the investigators propose to study children aged 2-17 years with small tonsils and OSA.

NCT ID: NCT06227572 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

Cognition After OSA Treatment Among Native American People (CATNAP)

CATNAP
Start date: May 2024
Phase: N/A
Study type: Interventional

This research project will develop and implement a motivational interviewing and electronic messaging intervention to address obstructive sleep apnea (OSA), positive airway pressure (PAP) adherence, and risk of Alzheimer's disease and related dementias in American Indians. The project will work with American Indian Elders, aged 50 years and older, from three Northern Plains Reservations and surrounding communities. A total of 300 American Indian elders with a confirmed OSA diagnosis and prescribed PAP therapy will be randomized to receive usual care consisting of PAP therapy alone (control condition) or usual care plus the culturally informed CATNAP MI component (intervention condition).

NCT ID: NCT06189755 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

MicroRNAs as Biomarkers for Obstructive Sleep Apnea

MIR-OSA
Start date: April 2024
Phase:
Study type: Observational

Although obstructive sleep apnea (OSA) is a common disorder, there are no blood biomarkers for identification and management of these patients. This project will study microRNAs in order to develop and validate blood biomarkers that are specific to OSA, useful for identification of cases with OSA, reflective of efficacy of therapy, and able to predict blood pressure response to treatment of OSA.