Goal-directed and Cue-dependent Behavior in Severe Obesity

Obesity Clinical Trial

— PIT_BS  

Official title:

Goal-directed and Cue-dependent Behavior in Severe Obesity

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04187066
• Other study ID #: PIT_BS
• Status: Recruiting
• Start date: August 1, 2019
• Est. completion date: December 31, 2023

Study information

• Verified date: May 2022
• Source: University Hospital Tuebingen
• Contact: Sabine Frank
• Phone: 004970712981193
• Email: s.frank[@]uni-tuebingen.de
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The current proposal aims to investigate implicit and explicit priming paradigms for changing cue-dependent and goal-directed nutritional behavior in participants with severe obesity before and after bariatric surgery as well as in a control group with normal weight.

Description:

Food choice and intake is a daily and throughout normal subject. However, for more and more people eating habits and the question of food choice are of increasing interest and in several cases even a problem. The prevalence of obesity has tripled in the last decades and it is even spoken of an obesity epidemic. Life style interventions to lose weight often fail on the long run, also because people fall back into former unhealthy eating habits. Bariatric surgery is a very effective procedure to reduce weight fundamentally.

Various factors influence our daily food choice, not all of which are apparent to ourselves. Thus, food choice might be goal-directed and therefore conscious and reflective, yet in other circumstances the choice to eat something specific might be based on cue dependent processes which are automatic and thus difficult to control. The aim of the current study is to investigate cue-dependent and goal-directed nutritional behavior as well as the effect of a health mindset induction in severe obesity as well as changes in such behaviors due to bariatric surgery.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 50
• Est. completion date: December 31, 2023
• Est. primary completion date: December 31, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• experimental: severe obesity

• control: normal weight

Exclusion Criteria:

• impaired cognitive functions, which might conflict with the task

• appropriate German

Related Conditions & MeSH terms

• Eating Behavior
• Habits
• Obesity
• Obesity, Morbid

Intervention

Behavioral:
• mindset induction
induction of a health mindset to measure changes in cue-dependent and goal-directed behavior

Locations

Country	Name	City	State
Germany	University Clinic of Tuebingen, fMEG Center	Tuebingen

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital Tuebingen

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	changes in food choice behavior due to substantial weight loss by bariatric surgery	changes in cue-dependent and goal-directed food choices assessed by the Pavlovian-to-instrumental transfer task	pre bariatric surgery, 1 month after bariatric surgery, 6 months after bariatric surgery