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Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Maintenance Therapy

Obesity Clinical Trial

Official title:
Behavioral and Pharmacologic Treatment of Binge Eating and Obesity

Clinical Trial Summary

This study will test the effectiveness and relative efficacy of naltrexone/bupropion medication as a maintenance therapy for the treatment of binge eating disorder (BED) in patients with obesity. This is a controlled test of whether, amongst responders to acute treatments, naltrexone/bupropion medication results in superior maintenance and longer-term outcomes compared with placebo.

Clinical Trial Description

Binge eating disorder (BED), the most prevalent formal eating disorder, is associated strongly with obesity and bio-psychosocial impairment. Improved treatments for patients with obesity and BED are needed that can produce sustained clinical outcomes and promote weight loss. This study (maintenance stage) RCT will provide new and novel findings from a controlled test, amongst responders to acute treatments, whether NB medication results in superior maintenance and longer-term outcomes than placebo. This is the first controlled test of maintenance pharmacotherapy for BED and will be only the third RCT for BED of any medication with follow-up after medication discontinuation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03047005
Study type Interventional
Source Yale University
Contact
Status Completed
Phase Phase 2/Phase 3
Start date August 28, 2017
Completion date December 16, 2022
View Details
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