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Clinical Trial Summary

The purpose of the study is to determine the effect of intranasal OXT caloric intake and eating behaviors in otherwise healthy obese adolescents.

The primary objective of this study is to determine the effects of intranasal administration of oxytocin on food intake in obese, pubertal or post-pubertal adolescents (13 to <18 years in girls, and 15 to <20 years in boys).


Clinical Trial Description

Participants will undergo a telephone screening and then, within 4 weeks, complete an in-person screening visit to determine eligibility. Then, within 4 weeks they will be randomized to either OXT or placebo. After a minimum 1-week (7-28 days) "washout," participants will cross-over to treatment with the other condition (i.e., placebo or OXT). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03497988
Study type Interventional
Source Children's Hospital of Philadelphia
Contact
Status Withdrawn
Phase Phase 2
Start date September 2018
Completion date June 2021

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