Clinical Trials Logo
NCT number NCT03454828
Study type Interventional
Source Yale University
Contact Nicola Santoro, PhD,MD
Phone 203-737-6356
Status Not yet recruiting
Phase N/A
Start date April 1, 2018
Completion date March 31, 2023

Clinical Trial Summary

The overarching goal of this project is to determine whether the effect of gut microbiota on human metabolism might be mediated by short chain fatty acids (SCFA) and whether the SCFA might modulate lipid metabolism.

Clinical Trial Description

This would be the first study determining the effect of SCFA synthesis on hepatic de novo lipogenesis and to assess whether and how isocaloric dietary changes (namely low carbohydrates) might modify the composition of the gut microbiota and reduce the synthesis of SCFA during adolescence, a sensitive period for the development of obesity.

Study Design

Related Conditions & MeSH terms

See also
  Status Clinical Trial Phase
Enrolling by invitation NCT02973815 - New Ulm at HOME (Healthy Offerings Via the Mealtime Environment), NU-HOME N/A
Recruiting NCT03170700 - Online Videos and New Feeding Content to Enhance a Current EFNEP Program N/A
Completed NCT03069274 - Sugar-sweetened Beverage Intake Substitution by Water to Prevent Overweight in Mexican Children N/A
Recruiting NCT03154255 - GOOD-DAY Trial in Paediatric Obesity N/A
Recruiting NCT03388411 - Nutritional Intake and Gut Microbiome N/A
Recruiting NCT03143660 - FITLINE: Pediatric Practice-based Obesity Intervention to Support Families N/A
Enrolling by invitation NCT03104777 - A Trial to Improve the Healthiness of Packed Lunches in Primary School Aged Children N/A
Enrolling by invitation NCT02956408 - Efficacy of Vitamin D Supplementation in Obese Children Phase 4
Completed NCT03261466 - BIFI-OBESE: Clinical Trial in Paediatric Obesity Phase 4
Not yet recruiting NCT03074929 - Improving Childhood Obesity-Related Behavior Change Through Better Risk Communication N/A
Recruiting NCT03432715 - Wellness Champions for Change N/A
Recruiting NCT03076073 - Ultrasonography of the Patellar Tendon and Achilles Tendon in Children Adolescent and Adults N/A
Recruiting NCT03141151 - Competency-based Approaches to Community Health N/A
Completed NCT03139773 - Nutrition Intervention to Measure Metabolic Response in Children N/A
Enrolling by invitation NCT03205293 - School-Based Intervention Program to Promote Healthy Eating and Physical Activity N/A
Not yet recruiting NCT03433456 - Healthy Homes, Healthy Habits N/A
Not yet recruiting NCT03109587 - Pilot Study of a Synbiotic in Pre-diabetic Adolescents N/A
Recruiting NCT03235440 - Feasibility of the Camp Power Up Program on Children's Body Weight and Quality of Life N/A
Recruiting NCT03245775 - A Trial of Two Family-based Childhood Obesity Treatment Programs N/A
Recruiting NCT03271801 - Skills Training Within a Family-based Obesity Treatment Intervention N/A