Non-Hodgkin's Lymphoma Clinical Trial
Official title:
A Multi-Center Phase II Study to Investigate the Safety and Activity of SDX-105 (Bendamustine) in Patients With Indolent Non-Hodgkin's Lymphoma (NHL) Who Are Refractory to Rituximab
Summary: As this is an open label study, all patients will receive SDX-105 by 30-60 minute
intravenous infusion on day 1 and day 2. Treatment will repeat every 21 days. Treatment can
continue for up to one year in the absence of disease progression or unacceptable toxicity.
Patients will be followed until disease progression.
Rationale: Drugs used in chemotherapy, such as SDX-105, use different ways to stop tumor
cells from dividing so they stop growing or die.
Purpose: This study will evaluate the effectiveness and safety in non-Hodgkin's lymphoma in
patients who are refractory to Rituxan.
n/a
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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