Clinical Trials Logo

Clinical Trial Summary

This is one multi-center, randomized, double-blind, parallel-group, placebo controlled Phase III clinical study to evaluate the efficacy and safety of LXI-15028 50 mg in treatment of non-erosive reflux disease in Chinese patients for 4 weeks.

Screening-eligible subjects will be randomized into LXI-15028 50mg group or placebo group at Visit 2 (Day 0) according to the ratio of 1:1 and receive study treatment for 4 weeks. They will start to take the investigational products in the following morning of Visit 2 (Day 1) and start to complete the subject's diary from the day of study treatment initiation. After 2 weeks of study treatment, subjects will return to the study site and complete Visit 3, after which receive study treatment for another 2 weeks and then complete Visit 4. On the day of Visit 4, subjects will not take any drug. All the subjects will be followed up by phone (Visit 5) at Day 28±3 after the last dose of study medication.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03591653
Study type Interventional
Source Shandong Luoxin Pharmaceutical Group Stock Co., Ltd.
Contact
Status Completed
Phase Phase 3
Start date October 29, 2018
Completion date November 26, 2019

See also
  Status Clinical Trial Phase
Active, not recruiting NCT05587322 - A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Non-Erosive Reflux Disease Phase 3
Completed NCT02556021 - Study to Evaluate the Safety and Efficacy of CJ-12420 in Patients With Non Erosive Reflux Disease Phase 3
Completed NCT03444883 - Phase III Study to Evaluate Safety and Efficacy of Ilaprazole in Patients With NERD Phase 3
Completed NCT00562094 - Efficacy of Pantoprazole in Patients Older Than 12 Years With Reflux Associated Sleep Disorders (PULS) N/A
Completed NCT00259077 - Four-week Omeprazole Treatment of Non-erosive Reflux Disease in a Japanese Population Phase 3
Enrolling by invitation NCT02149914 - The Changes of Ryodoraku and HRV After PPI Treatment in GERD Patients N/A
Terminated NCT00449813 - The CONQUEST-Study. Evaluation of Clinical Endpoints for Treatment-induced Changes in GERD-related Symptoms (BY1023/NL511) Phase 4
Completed NCT02081404 - Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective Study N/A
Completed NCT01797939 - Predictors of Proton Pump Inhibitor Response in Gastroesophageal Reflux Disease Patients N/A
Recruiting NCT04255693 - Real-life Study of Changes of Gastroesophageal Reflux Disease Manifestations Due to Behavioural and Diet Adherence N/A
Recruiting NCT04252144 - Study of Dietary Patterns and Food Diversity in Russian GERD Patients N/A
Recruiting NCT02892357 - Efficacy of Traditional Chinese Medicine Combined With Omeprazole in Patients With Non-erosive Reflux Disease Phase 1/Phase 2
Completed NCT01750437 - Phase 2 Clinical Trial to Investigate the Safety, Tolerability and Efficacy of YH1885L in Patients With Non-erosive Reflux Disease(NERD) Phase 2
Completed NCT01560910 - Detection of Minimal Change Esophagitis by I-scan N/A
Completed NCT00830115 - Pantoprazole 20/40 mg in the Treatment of Symptomatic Reflux Disease With Focus on Sleep Disorders N/A
Completed NCT00259051 - A Study to Investigate the Pharmacodynamic Effect After Four-week Omeprazole Treatment of Non-erosive Reflux Disease in a Japanese Population Phase 3
Not yet recruiting NCT04759378 - Comorbid Esophageal Disorders in IBS Patients N/A
Recruiting NCT05369884 - Efficacy and Safety of WPQW Granule for Overlap of NERD and IBS-D Early Phase 1
Recruiting NCT06121830 - Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Non-Erosive Gastroesophageal Reflux Disease (NERD) Phase 3
Terminated NCT02788591 - Confocal Endomicroscopy for Non-Erosive Reflux Disease Detection N/A