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Memantine and Post-mastectomy Neuropathic Pain — CLEMANTINE  

Neuropathic Pain Clinical Trial

Official title:
Effect of Oral Administration of Memantine in Pre and Post-surgery in the Prevention of Post-mastectomy Neuropathic Pain

Clinical Trial Summary

The aim of this study is to evaluate if memantine administered for four weeks starting two weeks before surgery induces a decrease in pain intensity at 3 months post-mastectomy.

Clinical Trial Description

This is a randomized, controlled, open-label study in patients undergoing mastectomy. Patients included in this trial will receive memantine or not. For patients in the "memantine" group, the treatment will be given in titration (maximum dose of 20 mg/day). Concerning the comparator group, patients will be followed in the same way as those in the "memantine" group except that they will not receive the study treatment. Whether it is the "memantine" group or the "usual care" group, visits will be scheduled under the usual following conditions of the participating center. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03686774
Study type Interventional
Source University Hospital, Clermont-Ferrand
Contact Lise LACLAUTRE
Phone 04 73 75 49 63
Email drci@chu-clermontferrand.fr
Status Not yet recruiting
Phase Phase 2
Start date February 15, 2019
Completion date January 31, 2022
View Details
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