Evaluation of the Tof Cuff for Perioperative Neuromuscular Transmission

Status Completed

Clinical Trial Summary

Acceleromyography (AMG) is the most wide spread used method to assess neuromuscular block during anesthesia. However AMG is known to be inaccurate when compared to the gold standard in neuromuscular transmission monitoring, electromyography (EMG). Furthermore when the patients arms require to be positioned next to the body and beneath surgical drapes, AMG measurements are often hindered and inaccurate. The TOF cuff is a new device which measures neuromuscular blockade at the upper arm with a blood pressure cuff. It overcomes the previously mentioned disadvantages of AMG. However, it validity compared to EMG and AMG has not yet fully been investigated. This study aims to compare the bias, limits of agreement and precision of the Train-of-Four cuff relative to AMG and EMG during recovery of moderate and deep neuromuscular block in patients with normal body mass index and morbidly obese patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Neuromuscular Blockade

Clinical Trial Details

NCT number	NCT03117387
Study type	Observational
Source	Leiden University Medical Center
Contact
Status	Completed
Phase
Start date	May 1, 2017
Completion date	July 1, 2020

View Details

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