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Pharmacokinetic and Pharmacodynamic of Rocuronium

Neuromuscular Blockade Clinical Trial

Official title:
Pharmacokinetic and Pharmacodynamic of Rocuronium Bromide Measured in Adductor Pollicis and Masseter Muscles.

Clinical Trial Summary

The purpose of this study is characterize the dose-effect relationship of rocuronium bromide at the adductor pollicis and masseter muscles using an pharmacokinetic-pharmacodynamic (PKPD) model. The hypothesis is that masseter muscle has a greater sensitivity to the neuromuscular blockers (rocuronium), faster onset and slower recovery profile than the adductor pollicis muscle.

Clinical Trial Description

n/a

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02376595
Study type Observational
Source Pontificia Universidad Catolica de Chile
Contact
Status Completed
Phase N/A
Start date March 2013
Completion date January 2015
View Details
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