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Necator Americanus Infection clinical trials

View clinical trials related to Necator Americanus Infection.

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NCT ID: NCT05372068 Recruiting - Diarrhea Clinical Trials

Cement flooRs AnD chiLd hEalth (CRADLE)

Start date: September 24, 2023
Phase: N/A
Study type: Interventional

This randomized trial in rural Bangladesh will measure whether installing concrete floors in households with soil floors reduces child enteric infection. The trial will randomize eligible households to receive concrete household floors or to no intervention and measure effects on child soil-transmitted helminth infection, diarrhea, and other enteric infections. The study will collect longitudinal follow-up measurements at birth and when children are ages 3, 6, 12, 18, and 24 months.

NCT ID: NCT03702530 Completed - Clinical trials for Necator Americanus Infection

Immunisation, Treatment and Controlled Human Hookworm Infection

ITCHHI
Start date: December 17, 2018
Phase: N/A
Study type: Interventional

24 healthy volunteers will be immunized with three times 50 L3 larvae or placebo followed by treatment with albendazol and subsequently challenged with twice 50 L3 larvae.

NCT ID: NCT03257072 Completed - Clinical trials for Necator Americanus Infection

Repeated Controlled Human Hookworm Infection

ReCHHI1
Start date: January 10, 2018
Phase: N/A
Study type: Interventional

Twenty-four healthy hookworm-naive volunteers will be exposed to 50 L3 Necator americanus larvae for a maximum of three times.

NCT ID: NCT03126552 Completed - Clinical trials for Necator Americanus Infection

Establishing a Controlled Human Hookworm Infection Model at Leiden University Medical Center

CHHIL
Start date: April 1, 2017
Phase: N/A
Study type: Interventional

Four healthy hookworm-naive volunteers will be exposed to 50 L3 Necator americanus larvae once and will retain infection for up to 2 years.

NCT ID: NCT01350271 Completed - Clinical trials for Necator Americanus Infection

Comparative Efficacy of Different Mebendazole Polymorphs in the Treatment of Soil-transmitted Helminth Infections

Start date: May 2011
Phase: Phase 3
Study type: Interventional

Mebendazole tablets which are produced by most pharmaceutical manufacturers, including the State Pharmaceutical Manufacturing Corporation (SPMC) of Sri Lanka, contain a mixture of polymorphs A and C. However, there is some evidence to show that mebendazole polymorph C is the only form effective against the soil-transmitted helminths. This protocol describes a stratified, randomized, placebo-controlled trial that examined the efficacy of different mebendazole polymorphs produced by the SPMC in the treatment of hookworm infections.