Nausea Clinical Trial
Official title:
A Korean Multicenter, Randomized, Double-Blind, Clinical Trial to Evaluate the Efficacy and Tolerability of Aprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting in the First Cycle of Moderately Emetogenic Chemotherapies (MEC, Non-AC Regimes) With Broad Range of Tumor Types (KMEC Study)
This is an efficacy and safety study to compare aprepitant with ondansetron for the
prevention of nausea and vomiting in the first cycle of moderately emetogenic chemotherapy
(MEC) in participants with solid tumors. MECs include a number of commonly used cancer
chemotherapeutic drugs including: oxaliplatin-based, irinotecan-based, and carboplatin-based
regimens.
The primary hypothesis of this study is that the Aprepitant Regimen is superior to the
Control (ondansetron) Regimen with respect to the percentage of participants with No Vomiting
Overall (in the 120 hours following initiation of MEC) in participants with solid tumors.
n/a
Status | Clinical Trial | Phase | |
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