Olfactory Change After Chemo-radiotherapy for Nasopharyngeal Carcinoma

Status Recruiting

Clinical Trial Summary

This is an observational cohort study aimed to explore the changes of olfactory function at multiple time points from baseline to 1 year after radiotherapy among the local advanced nasopharyngeal carcinoma patients.

Clinical Trial Description

Newly-diagnosed patients with stage III or IV non-metastatic Nasopharyngeal Carcinoma (AJCC 8th) will be recruited. Olfactory function of consecutive patients with nasopharyngeal carcinoma was assessed prospectively before treatment and serially up to 1 year after radiotherapy by the Sniffin' Sticks olfactory function test and by The Questionnaire of Olfactory Disorders (QOD) as well as a patient symptom visual analogue scale. The change in olfactory function and it's influence factors in NPC patients who receiving induction chemotherapy with concurrent chemoradiotherapy will be investigated. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05146050
Study type	Observational [Patient Registry]
Source	Sun Yat-sen University
Contact	Haiqiang Mai, Dr
Phone	86-20-8734-3643
Email	maihq@mail.sysu.edu.cn
Status	Recruiting
Phase
Start date	December 8, 2021
Completion date	December 1, 2022

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