Myocardial Infarction Clinical Trial
Official title:
Predictive Value of Epicardial Fat Thickness for Disease Severity in Coronary Artery Disease Patients
is to test the hypotheses that epicardial adipose tissue can be a marker of severity of coronary artery disease in myocardial infarction patients
epicardial adipose tissue is defined as the adipose tissue between the visceral pericardium
and the outer margin of the myocardium which can be considered an endocrine organ that
secretes pro-inflammatory and anti-inflammatory cytokines and chemokines including
adiponectin.as investigators know, inflammatory response is an important factor in the
coronary atherogenesis. Therefore,epicardial adipose tissue is likely to be connected with
the severity of coronary artery disease.Recent studies showed that the thickness of the
epicardial adipose tissue in patients with coronary artery disease was greater than that with
normal coronary arteries.
epicardial adipose tissue will be assessed using transthoracic echocardiography and cardiac
magnetic resonance which allows for an accurate volumetric quantification of epicardial fat.
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