Effects of Task-oriented Training on Functional Mobility and Fatigue in Patients With Multiple Sclerosis

Multiple Sclerosis, Relapsing-Remitting Clinical Trial

Official title:

Effects of Task-oriented Training on Functional Mobility and Fatigue in Patients With Multiple Sclerosis

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03497468
• Other study ID #: kunal
• Status: Not yet recruiting
• Phase: N/A
• First received: April 3, 2018
• Last updated: April 12, 2018
• Start date: April 2018
• Est. completion date: June 2018

Study information

• Verified date: April 2018
• Source: Bezmialem Vakif University
• Contact: Kamer Unal-Eren, PT, PhD
• Phone: +902125232288
• Email: kamerunals[@]yahoo.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Multiple Sclerosis (MS) is inflammatory, demyelinating and autoimmune disease of the central nervous system. It is usually seen with relapses and genetic and environmental factors play a role in the etiology. Neurological symptoms seen in MS restrict the patient's daily activity and social role participation. Mobility problems and fatigue are the most important reasons of role limitations and decreased quality of life. The importance of exercise training in disease management has been emphasized in recent years. However, few studies have investigated the effects of task-oriented trainings on symptoms of the disease. The aim of this sudy is to investigate the effects of task-oriented training additional to combined exercise training on functional capacity, mobility, balance, fatigue and quality of life in patients with MS.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 34
• Est. completion date: June 2018
• Est. primary completion date: June 1, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Multiple Sclerosis diagnosis

• Expanded Disability Status Scale > 5,5

• No cognitive problems

• No relapses in the last 3 months

• No other neurological or chronic disease

Exclusion Criteria:

• Relapse during the intervention

• Exercise intolerance

Related Conditions & MeSH terms

• Fatigue
• Multiple Sclerosis
• Multiple Sclerosis, Relapsing-Remitting
• Sclerosis

Intervention

Other:
• Combined exercise training
Aerobic training with cycle ergometer %60-80 of maximal Heart Rate, submaximal level, strengthening of the major muscles of upper and lower extremities
• Task-oriented training
Functional reaching, walking on different obstacles and floor,sitting and standing on different levels and surface,walking around obstacle, climbing stairs with different height and surface

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Bezmialem Vakif University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Functional capacity	Change from baseline functional capacity with six minute walking test	6 weeks
Secondary	dynamic gait skills	Change from baseline functional mobility with dynamic gait index	6 weeks
Secondary	limitation of gait	Change from baseline functional mobility with MS walking scale-12	6 weeks
Secondary	dynamic balance and fall risk	Change from baseline functional mobility with timed up and go test	6 weeks
Secondary	sitatic balance	Change from baseline balance with functional reach test	6 weeks
Secondary	dynamic balance	Change from baseline balance with berg balance scale	6 weeks
Secondary	severity of fatigue	Change from baseline fatigue with fatigue severity scale	6 weeks
Secondary	impact of fatigue	Change from baseline fatigue with fatigue impact scale	6 weeks
Secondary	Quality of life	Change from baseline quality of life with MS quality of life instrument-54	6 weeks