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Clinical Trial Summary

Recruitment to phase I of the PANTHER trial is complete.

Phase II, is to evaluate the best overall response rate for AZD8931 + FOLFIRI treatment.


Clinical Trial Description

PANTHER is a registered phase I/phase II trial in patients with recurrent or metastatic colorectal cancer.

The phase II part of the study will be a single arm trial. Patients will receive AZD8931 (an EGFR/ERBB inhibitor) in combination with FOLinic acid, Fluorouracil and IRInotecan (FOLFIRI), Treatment will be given in two-weekly cycles. Phase II's primary objective is to evaluate the Best overall response ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01862003
Study type Interventional
Source University College, London
Contact
Status Completed
Phase Phase 2
Start date May 2014
Completion date August 2, 2019

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