Mesenteric Vein Thrombosis Clinical Trial
Official title:
Acute Mesenteric Venous Thrombosis.. in Assiut University Hospital Management Controversies
Initial treatment in the management of acute mesenteric vein thrombosis (MVT) is controversial. Some authors have proposed a surgical approach, whereas others have advocated medical therapy (anticoagulation). In this study, the investigators analyzed and compared the results obtained with surgical and medical treatment to determine the best initial management for this disease.
Mesenteric venous thrombosis (MVT) is increasingly recognized as a cause of mesenteric
ischemia. it must be distinguished from arterial and non occlusive types of ischemia, it
accounts for 5% to 15% of all cases of mesenteric ischemia. Patients may have evocative
signs,such as abdominal pain that is out of proportion to physical signs, nausea, or
vomiting. However, a clinical diagnosis is often difficult because abdominal symptoms are non
specific and high index of suspicion is often required for diagnosis.(1) Primary MVT
accounted for 25% to 55% of cases in early studies, but recent reports show decline in
primary MVT because of improvements in the diagnosis of hypercoagulable states.(2) Advances
in new imaging techniques also have enabled early recognition of this disease without or
before laparotomy.(3-5 ) Fortunately , there is no consensus about the initial management of
MVT; Some authors have proposed an aggressive surgical approach (6) while others have
advocated an initial conservative management with anticoagulation and close monitoring . ( 7)
similarly,issue of second look laparotomy,mandatory or selective is yet not resolved.
The present study is prompted to analyze our experience in an effort to resolve these
controversies and the results obtained will be assessed to determine the best management
strategy for this uncommon disease.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT02627053 -
Treatment of Splanchnic Vein Thrombosis With Rivaroxaban. A Pilot, Prospective Cohort Study
|
Phase 3 |