IMCgp100-401 Rollover Study

Status Terminated

Clinical Trial Summary

Clinical Trial Description

IMCgp100-401 is a rollover study that is designed to provide continued access to IMCgp100 for eligible participants with advanced melanoma who have previously participated in an IMCgp100 study (parent study). Parent studies that are eligible for participants to continue to receive IMCgp100 in this rollover study must have completed and satisfied its primary endpoints or have been terminated by the Sponsor for reasons other than safety.

Eligible participants will have tolerated IMCgp100 for a minimum of 4 weeks of dosing without significant toxicities that would preclude further dosing in the opinion of the principal investigator or Sponsor. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02889861
Study type	Interventional
Source	Immunocore Ltd
Contact
Status	Terminated
Phase	Phase 2
Start date	January 11, 2017
Completion date	April 22, 2019

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04229277` - Fast Track Diagnosis of Skin Cancer by Advanced Imaging	N/A
Completed	`NCT03653819` - High Intensity Interval Training (HIIT) for Patients With Cancer-related Lymphedema in the Lower Limbs	N/A
Active, not recruiting	`NCT04074096` - Binimetinib Encorafenib Pembrolizumab +/- Stereotactic Radiosurgery in BRAFV600 Melanoma With Brain Metastasis	Phase 2
Completed	`NCT02935790` - Selective HDAC6 Inhibitor ACY-241 in Combination With Ipilimumab and Nivolumab	Phase 1
Recruiting	`NCT05478876` - Carbon Ion Radiation Therapy in the Treatment of Mucous Melanomas of the Female Lower Genital Tract	N/A
Completed	`NCT01211262` - Study to Assess the Tolerability of a Bispecific Targeted Biologic IMCgp100 in Malignant Melanoma	Phase 1
Recruiting	`NCT03649529` - Treatment of Malignant Melanoma With GPA-TriMAR-T Cell Therapy	Early Phase 1
Completed	`NCT03278665` - 4SC-202 in Combination With Pembrolizumab in Patients Primary Refractory/Non-responding to Prior Anti-PD-1 Therapy	Phase 1/Phase 2
Completed	`NCT04452214` - A Study of the Safety and Tolerance of CAN04 and Pembrolizumab in Combination With and Without Carboplatin and Pemetrexed in Subjects With Solid Tumors	Phase 1
Terminated	`NCT02709889` - Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors	Phase 1/Phase 2
Completed	`NCT01455259` - Phase I/IIa AdCD40L Immunogene Therapy for Malignant Melanoma and Other Solid Tumors	Phase 1/Phase 2
Completed	`NCT00978913` - Transfected Dendritic Cell Based Therapy for Patients With Breast Cancer or Malignant Melanoma	Phase 1
Completed	`NCT00232726` - Clinical Study of Previously Untreated Patients With Malignant Melanoma	Phase 2
Completed	`NCT00336986` - Efficacy Study of IL-21 to Treat Metastatic Melanoma	Phase 2
Completed	`NCT00350597` - GM-CSF as Adjuvant Therapy of Melanoma	Phase 2
Completed	`NCT02523313` - Immunotherapy With Nivolumab or Nivolumab Plus Ipilimumab vs. Double Placebo for Stage IV Melanoma w. NED	Phase 2
Completed	`NCT03545334` - Lymph Node Identification in Skin Malignancy Using ICG Transcutaneously Study	N/A
Completed	`NCT04253574` - Comparison of PET/CT and Ultrasound in Staging of Malignant Melanoma
Completed	`NCT00179608` - Study of the Combination of Lenalidomide and DTIC (Dacarbazine) in Patients With Metastatic Malignant Melanoma Previously Untreated With Systemic Chemotherapy	Phase 1
Terminated	`NCT00104884` - FR901228 in Treating Patients With Unresectable Stage III or Stage IV Malignant Melanoma	Phase 2