Lymphoma Clinical Trial
Official title:
Health Status and Quality of Life in Patients With Early Stage Hodgkin's Disease: A Companion Study to SWOG-9133
RATIONALE: Quality-of-life assessment in patients undergoing cancer treatment may help
determine the intermediate- and long-term effects of treatment on patients with cancer.
PURPOSE: This clinical trial studies the impact of therapy on the health status and quality
of life of patients with stage I or stage II Hodgkin's disease who are receiving radiation
therapy with or without chemotherapy.
OBJECTIVES: I. Evaluate prospectively the health status and quality of life of patients with
Stage I/IIA Hodgkin's disease randomized on protocol SWOG-9133 (CLB-9391) to treatment with
subtotal nodal irradiation with vs. without 3 courses of doxorubicin/vinblastine. II.
Describe the short-term effects of these treatments on these patients and compare their
impact on quality of life (i.e., patient symptom status, health status, fatigue). III.
Evaluate the intermediate and long-term effects of these treatments on these patients and
compare their impact on quality-of-life outcomes over 5 years.
OUTLINE: Quality-of-Life Assessment. Cancer Rehabilitation Evaluation System Short Form,
CARES-SF; Symptom and Personal Information Questionnaire (including Symptom Distress Scale,
MOS SF-36 Fatigue Scale, MOS SF-36 Health Perception Rating, Demographics); Cover Sheet.
PROJECTED ACCRUAL: Approximately 500 patients will be accrued over 7 years.
;
Observational Model: Case-Only, Time Perspective: Prospective
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