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A Study of SHR-1210 in Combination With BP102 in Subjects With Non-squamous NSCLC

Lung Neoplasms Clinical Trial

Official title:
An Open-label, Single-arm, Multi-center, Phase 2 Study to Evaluate SHR-1210 Combination With BP102 in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer Whose PD-L1 Positive and EGFR/ALK Wild Type.

Clinical Trial Summary

SHR-1210 is a humanized anti-PD1 IgG4 monoclonal antibody. This is a Phase II, multicenter, open-label study designed to evaluate the safety and efficacy of SHR-1210 with BP102 in subjects who are chemotherapy naive and have Stage IIIB~IV non-squamous NSCLC. The primary end points are ORR and PFS. In this study, subjects will receive SHR-1210 combined with BP102 until progression or unacceptable toxicity (SHR-1210 or BP102 for a maximum of 2 years).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03666728
Study type Interventional
Source Jiangsu HengRui Medicine Co., Ltd.
Contact
Status Terminated
Phase Phase 2
Start date November 30, 2018
Completion date March 11, 2020
View Details
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