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Longitudinal Evaluation of Microbial and Host Signatures During Immunotherapy for Lung Cancer

Lung Cancer Clinical Trial

Official title:
Longitudinal Evaluation of Microbial and Host Signatures During Immunotherapy for Lung Cancer

Clinical Trial Summary

This study will prospectively collect airway, stool, and blood samples on 80 subjects with lung cancer undergoing immunotherapy. Investigators will evaluate airway/stool microbial signatures associated with local (lower airway) and systemic (blood) immune tone.They will then study whether microbiota and/or host signatures predict subjects' response by longitudinal assessment of the progression free survival. They will also repeat sampling after 8 weeks of immunotherapy to expand our mechanistic understanding of the response to treatment.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04063501
Study type Observational
Source NYU Langone Health
Contact Lira Gutierrez
Phone 212-263-6181
Email Lira.Gutierrez@nyulangone.org
Status Recruiting
Phase
Start date February 9, 2021
Completion date February 2026
View Details
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