Prognostic Factors After Liver Transplantation

Liver Diseases Clinical Trial

Official title:

Prognostic Factors After Liver Transplantation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05018741
• Other study ID #: 191244
• Status: Completed
• Start date: January 1, 2002
• Est. completion date: December 31, 2019

Study information

• Verified date: August 2021
• Source: Changhua Christian Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The study retrospectively reviewed the medical records of patients who received adult liver transplantation in Changhua Christian hospital from 2002 to 2019. We collected their personal data about liver disease, laboratory data about liver function, pre-transplant evaluation and post-transplant outcome. We investigate what prognostic factors may contribute a good survival outcome, and improve our clinical practice.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 600
• Est. completion date: December 31, 2019
• Est. primary completion date: December 31, 2019
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• patients who received adult liver transplantation in Changhua Christian hospital from 2002 to 2019

Exclusion Criteria:

• patients who did not have suitable donor for liver transplantation

Related Conditions & MeSH terms

• Liver Diseases
• Liver Transplant; Complications

Intervention

Procedure:
• liver transplantation
liver transplantation for chronic liver disease or acute liver failure

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Changhua Christian Hospital

References & Publications (3)

Chang Y, Cho Y, Lee JH, Lee YB, Cho EJ, Yu SJ, Sinn DH, Kim BH, Kim SH, Yi NJ, Lee KW, Kim JM, Park JW, Kim YJ, Yoon JH, Joh JW, Suh KS. Comparison of Models for Tumor Recurrence after Liver Transplantation for the Patients with Hepatocellular Carcinoma: A Multicenter Long-Term Follow-Up Study. Cancers (Basel). 2019 Sep 3;11(9). pii: E1295. doi: 10.3390/cancers11091295. — View Citation

Lee SG, Hwang S, Moon DB, Ahn CS, Kim KH, Sung KB, Ko GY, Park KM, Ha TY, Song GW. Expanded indication criteria of living donor liver transplantation for hepatocellular carcinoma at one large-volume center. Liver Transpl. 2008 Jul;14(7):935-45. doi: 10.1002/lt.21445. — View Citation

Mazzaferro V, Llovet JM, Miceli R, Bhoori S, Schiavo M, Mariani L, Camerini T, Roayaie S, Schwartz ME, Grazi GL, Adam R, Neuhaus P, Salizzoni M, Bruix J, Forner A, De Carlis L, Cillo U, Burroughs AK, Troisi R, Rossi M, Gerunda GE, Lerut J, Belghiti J, Boi — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	number of participants with morbidity and mortality after surgery	post-operative complications which requiring interventions, related to organ failure and hospital mortality	upto one month after surgery
Secondary	long-term survival rate	1,5 year survival rate	upto 5 years after surgery