Clinical Trials Logo

Clinical Trial Summary

A pilot study to evaluate the effect of incorporating sublingual sufentanil into our perioperative opioid regimen for ambulatory orthopedic surgery.


Clinical Trial Description

A pilot study to evaluate the effect of incorporating sublingual sufentanil into our perioperative opioid regimen for ambulatory orthopedic surgery. The results will help us estimate treatment effect and determine sample size for a subsequent full-scale clinical trial. Primary Endpoint: total amount of fentanyl consumed during hospital admission. Secondary Endpoints: 1) phase I recovery time; and, 2) time to fitness for discharge. Exploratory Endpoints: 1) intraoperative hemodynamics; 2) intraoperative opioid use; 3) intraoperative sevoflurane use; 4) postoperative pain; 5) postoperative sedation and cognitive recovery 6) time to first request for analgesia; and, 7) incidence of nausea and vomiting between the end of anesthesia and hospital discharge. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04561375
Study type Interventional
Source The Cleveland Clinic
Contact
Status Terminated
Phase Phase 4
Start date December 11, 2020
Completion date July 1, 2022

See also
  Status Clinical Trial Phase
Recruiting NCT06098391 - Results at More Than 10 Years of Meniscal Sutures Without Avivement
Completed NCT04467359 - Application of Rapid Rehabilitation Nursing in Perioperative Rehabilitation of Knee Arthroscopy N/A
Not yet recruiting NCT05090670 - The Impact of Germanium-Embedded Knee Brace on Patient Recovery After Knee Arthroscopy N/A
Completed NCT05822973 - Sutures for Treatment of Knee Arthroscopy N/A
Not yet recruiting NCT06112223 - Preemptive Oral Gabapentin and Tramadol on Postoperative Pain After Knee Arthroscopy N/A
Completed NCT04130412 - Open Versus Arthroscopic Release for Lateral Patellar Compression Syndrome: Comparative Study N/A
Completed NCT04308772 - Web-Based Physiotherapy Following Knee Arthroscopy N/A
Terminated NCT03365752 - Chloroprocaine Spinal for Outpatient Knee Surgery Phase 2
Not yet recruiting NCT03926000 - Pregabalin Premedication for Knee Arthroscopy N/A
Withdrawn NCT01112878 - Oral Clonidine & Gabapentin: Improving Recovery and Pain Management After Outpatient With Major Orthopedic Surgery Phase 4
Completed NCT00799149 - Etoricoxib Versus Gabapentin for Knee Arthroscopy Phase 4
Terminated NCT03173326 - Patient Satisfaction and Postoperative Analgesia Between Subarachnoid Block With 2-chloroprocaine Versus General Anesthesia for Knee Arthroscopy N/A
Terminated NCT02174770 - Blood Flow Restriction Training in Rehabilitation Patients N/A
Completed NCT01247376 - Temperature Sensitive Release of PGE2 and Diminished Energy Requirements in Synovial Tissue With Postoperative Cryotherapy - A Prospective Randomised Study After Knee Arthroscopy N/A
Withdrawn NCT02294045 - Analysis of Joint Sounds in the Diagnosis of Knee Disorders
Completed NCT04566250 - Non-Opioid Prescriptions After Arthroscopic Surgery in Canada (NO PAin) N/A
Completed NCT02411890 - Postoperative Pain Between ACB and FNB After ACLR Phase 4
Completed NCT02730845 - Intra-articular Versus Intravenous Dexmedetomidine in Arthroscopic Knee Surgeries Under Local Anesthesia N/A
Completed NCT05580640 - Investigating the Efficacy of Osteopathic Manipulative Treatment on Gait Dysfunction Following Knee Surgery N/A
Completed NCT00803725 - Spinal Mepivicaine With Fentanyl for Outpatient Knee Arthroscopy N/A