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Keratotic Nodular Size clinical trials

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NCT ID: NCT04693000 Active, not recruiting - Clinical trials for Keratotic Nodular Size

Use of Topical Solasodine of Solanum Melongena Peel Origin in the Treatment of Palmar Arsenic Keratosis

Start date: September 23, 2018
Phase: Phase 2
Study type: Interventional

Arsenic is one of the largest mass poisonings in Bangladesh. Arsenic keratosis of the palm and sole is a common feature of arsenicosis. Brinjal or eggplant ubiquitous vegetable found in different parts of the world, including Bangladesh, scientifically known as Solanum melongena. A study showed ointment containing crude extract of Solanum melongena peel origin is effective in arsenic keratosis. Solasodine is one of the active compounds of Solanum melongena peel. In the current study, an ointment containing a single compound solasodine isolated from Solanum melongena peel . The ointment made from solasodine extract was distributed among arsenic keratosis patients to see the effect.

NCT ID: NCT04686474 Recruiting - Clinical trials for Keratotic Nodular Size

Effect of the Compound Extracted From Azadirachta Indica Leaves in the Treatment of Arsenical Keratosis

Start date: October 20, 2019
Phase: N/A
Study type: Interventional

Prepare an ointment from Azadirachta indica leaves extract and its apply on palmer arsenical keratosis patient, for 12 weeks. After intervention, effect of the ointment will be observed by measuring the nodule (before and after apply the ointment)

NCT ID: NCT04686461 Recruiting - Clinical trials for Keratotic Nodular Size

Effect of Thymoquinone Extracted From Nigella Sativa in the Treatment of Arsenical Keratosis

Start date: October 20, 2019
Phase: N/A
Study type: Interventional

Prepare an ointment from Nigella sativa seeds extract and apply it over palmer arsenical keratosis patient for 12 weeks. After than the effect of the ointment will be observed by measuring the keratotic nodular size before and after the intervention.

NCT ID: NCT04608461 Recruiting - Clinical trials for Keratotic Nodular Size

Effect of Pumpkin Seeds in the Treatment of Moderate to Severe Palmar Arsenical Keratosis

Start date: September 17, 2019
Phase: Phase 2
Study type: Interventional

Arsenicosis is a major health problem in Bangladesh. Long term exposure of arsenic causes keratosis of palm which reduce working capacity of patient. It also causes massive skin lesions like Bowen's disease which has a risk to develop squamous cell carcinoma. Pumpkin seed is well known for its antioxidant and anticancer properties. So this study will be conducted to identify the compound from pumpkin seeds and to see its outcome on keratosis.

NCT ID: NCT03641079 Recruiting - Clinical trials for Keratotic Nodular Size

Identification of Compound From Brinjal Peel Extract in the Treatment of Palmar Arsenical Keratosis and Bowen's Disease

Start date: September 16, 2017
Phase: Phase 2
Study type: Interventional

Arsenicosis is a major health problem in Bangladesh. Long term exposure of arsenic causes keratosis of palm which reduce working capacity of patient. It also causes invasive skin lesions like Bowen's disease which has a risk to develop squamous cell carcinoma. Brinjal peel is well known for its antioxidant and anticancer properties. So this study will be conducted to identify the compound from brinjal peel extract and to see its outcome on keratosis and Bowen's disease.

NCT ID: NCT03632733 Recruiting - Clinical trials for Keratotic Nodular Size

Effects of Antimicrobials on the Altered Skin Flora in Arsenical Keratosis

Start date: January 21, 2018
Phase: Phase 2
Study type: Interventional

It had been found in certain studies that there is an alteration of normal skin flora in patients with arsenical keratosis. The relationship between such altered skin flora and development of keratosis in arsenicosis is not established or explored.There is no such study where effects of antimicrobials have been evaluated as the treatment of arsenical keratosis. So the present study is designed to see the effects of antimicrobials on the altered skin flora (Enterobacter and Aspergillus) in patients with palmar arsenical keratosis.