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Keloid clinical trials

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NCT ID: NCT02079168 Completed - Keloid Clinical Trials

A Study to Evaluate the Effectiveness and Safety of RXI-109 on the Outcome of Keloid Excision Surgery in Healthy Adults

Start date: March 2014
Phase: Phase 2
Study type: Interventional

To evaluate the effectiveness of RXI-109 in reducing the recurrence of keloid formation following elective keloid excision.

NCT ID: NCT02063243 Completed - Keloid Clinical Trials

Intralesional Cryotherapy With a Argon Gas Based Device for the Treatment of Keloid and Hypertrophic Scars

Start date: January 2010
Phase: N/A
Study type: Interventional

This prospective evaluation studies the effectiveness of Intralesional (IL) cryotherapy with a argon gas based device in treating keloids and hypertrophic scars in population consisting of all Fitzpatrick skin type patients

NCT ID: NCT02005055 Completed - Keloid Clinical Trials

High Dose Rate Brachytherapy for Treatment of Keloids

Start date: January 2003
Phase: N/A
Study type: Observational

This prospective study evaluates the outcome of surgical excision with adjuvant high-dose-rate brachytherapy for the treatment of recalcitrant keloids. Main outcomes are recurrence rate, scar quality and physical complaints.

NCT ID: NCT01994616 Completed - Keloid Clinical Trials

Prospective Evaluation of the Use of Intralesional Cryotherapy for Treatment of Keloid and Hypertrophic Scars

Start date: January 2009
Phase: N/A
Study type: Observational

This prospective evaluation studies the effectiveness of IL cryotherapy in treating keloids and hypertrophic scars in a large population of mixed Fitzpatrick skin types.

NCT ID: NCT01941914 Completed - Keloid Clinical Trials

Calcium Electroporation for the Treatment of Keloids

Start date: August 2013
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the effect of calcium electroporation on keloids.

NCT ID: NCT01861119 Completed - Clinical trials for Hypertrophic or Keloid Scars

Silicone Gel Versus Onion Extract Gel as Prevention for Postsurgical Scars

Start date: April 1, 2013
Phase: Phase 3
Study type: Interventional

Hypertrophic or keloid scars develop for about 39% to 68% of patients after surgery. The subjective opinion of the patient regarding the scar will often constitute the standard for judging the success or failure of the procedure. Surgical scars are not only a cosmetic concern but they can also cause pain, itching, discomfort, contracture, and other functional impairment. Various treatment options exists for treating hypertrophic scars and keloids, including intralesional steroid injection, dermabrasion, pressure therapy, surgical excision, radiotherapy, cryotherapy, pulse dye, and carbon dioxide laser ablation. However, these treatments often require multiple visits and have limited success. Therefore, prevention and early recognition of hypertrophic scars and keloids are very important in their management. Among preventive treatments available, silicone gel and onion extract gel have been marketed as products to improve the appearance and texture of surgical scars. Despite its popularity, data demonstrating the efficacy of these gels are lacking. Furthermore, there is no comparative study of silicone gel and onion extract gel for preventing postsurgical hypertrophic or keloid scars. The investigators therefore conducted this randomized controlled trial to compare the efficacy of silicone gel and onion extract gel for the prevention of postsurgical hypertrophic scars. The investigators also compared patient compliance and side effect between two topical gels.

NCT ID: NCT01789346 Completed - Scar Clinical Trials

Pilot Study of a Novel 532nm KTP Laser for the Treatment of Fresh Surgical Scars

Start date: February 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of the 532nm potassium titanyl phosphate (KTP) laser in comparison with the 595nm pulsed-dye laser (PDL) for the treatment of fresh surgical scars.

NCT ID: NCT01706861 Completed - Earlobe Keloids Clinical Trials

A Post Market Study Evaluating the Safety, Device Perfomance and Possible Emergent Risks of Celotres in Preventing Recurrence in Keloid Lesions Treated Adjunctive to Surgical Excision

EURO KLEAR
Start date: September 2012
Phase: N/A
Study type: Interventional

The objective of the study is to actively gather additional information on safety, device performance and possible emergent risks following the use of Celotres in a post-market setting when used to reduce the recurrence rate, volume, appearance and/or symptoms associated with keloid scarring in subjects undergoing surgical excision of keloids as compared to the scientific literature.

NCT ID: NCT01446770 Completed - Keloid Clinical Trials

Evaluation of the Initial Safety and Efficacy of Keloid Lesions Treated With MF-4181

Start date: November 2010
Phase: Phase 2
Study type: Interventional

The objective of the study is to evaluate the initial safety and efficacy of MF-4181, a hydrogel scaffold, in the reduction of the volume, appearance, and/or symptoms associated with keloid scarring in subjects undergoing surgical revision of keloid scars.

NCT ID: NCT01176877 Completed - Keloid Scar Clinical Trials

Assessing and Improving Patient Knowledge About Keloid Scars (Keloids)

Start date: August 2010
Phase: N/A
Study type: Interventional

The purpose of this study is: - to identify how knowledge about keloid scars and self-treatments differs between patients who use the Internet as a source of information and patients who do not - to determine if patients who are at a high risk of developing additional keloid scars are more or less likely to change their behavior based on an educational information talk about keloid scar prevention