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Clinical Trial Summary

The primary aim of the study is to investigate the relationships among FVIII, t-PA/PAI-1, MMP-9 levels, and intracranial hemorrhage after thrombolysis with alteplase using a combined analysis.


Clinical Trial Description

Patients with acute ischemic stroke treated with alteplase within 4.5 hours after the onset of stroke symptoms will be recruited in this study. All participants will be divided into two groups according to whether intracranial hemorrhage occurred within 3 days after treatment with alteplase for analysis. Differences in FVIII, t-PA/PAI-1, and MMP-9 levels before and after thrombolytic therapy will be examined in both groups. This study will be conducted at Zhujiang Hospital of Southern Medical University, Nanfang Hospital of Southern Medical University, and the First Affiliated Hospital of Jinan University. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03733223
Study type Observational
Source Zhujiang Hospital
Contact Shuai He, Doctor
Phone 862062783372
Email hs43555@qq.com
Status Recruiting
Phase
Start date October 12, 2018
Completion date December 2020

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