Irritable Bowel Syndrome Clinical Trial
Official title:
The Effect of a Symbiotic LCA Yoghurt on Health-related Quality of Life and the Symptoms of Irritable Bowel Syndrome in Adults: A Randomized, Double-blind, Placebo Controlled, Multicentre Clinical Trial
This study evaluates the effect of a symbiotic fermented milk on health-related quality of life and irritable bowel syndrome (IBS) symptoms in patients with constipation-predominant IBS.
Irritable bowel syndrome (IBS) is one of the most common digestive disorders in the
developed world which. It is associated to numerous symptoms, of which the most
characteristic are recurrent pain or discomfort in the abdominal region, changes and
difficulties related to bowel movements, and bloating. Although not dangerous, the disease
may significantly impair the patients' quality of life. Treatment is symptomatic, but
currently not very efficient. The use of probiotics in the treatment of IBS is a promising
approach and has been the subject of much research in the last two decades.
The purpose of this randomized, placebo-controlled study is to assess changes in
health-related quality of life in patients with constipation-predominant IBS after regular
consumption of symbiotic fermented milk (containing probiotics and dietary fibres) and to
assess its effects on some symptoms, like abdominal pain or discomfort, bloating, and
chronic constipation.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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