Clinical Trials Logo
  1. Home
  2. Intubation, Intratracheal
  3. NCT01880931
  4. Details
NCT01880931 Clinical Trial

The Effect Site Concentration of Remifentanil for Preventing QTc Interval Prolongation During Intubation in Normotensive and Hypertensive Patients

Intubation, Intratracheal Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01880931
Other study ID # 4-2013-0239
Secondary ID
Status Completed
Phase N/A
First received June 16, 2013
Last updated April 8, 2015
Start date June 2013
Est. completion date November 2014

Study information
Verified date April 2015
Source Severance Hospital
Contact n/a
Is FDA regulated No
Health authority Korea: Institutional Review Board
Study type Interventional

Clinical Trial Summary

To find out the effect site concentration of remifentanil for preventing QTc interval prolongation during intubation under propofol-remifentanil anesthesia in normotensive and hypertensive patients

Description:

It is known that anesthetic agents can influence the QTc. In addition, tracheal intubation during induction can stimulates sympathetic activity, which, as a results, prolong the QTc interval. Therefore, the aim of study is to find out the effect site concentration of remifentanil for preventing QTc interval prolongation during intubation under propofol-remifentanil anesthesia in normotensive and hypertensive patients.

Recruitment information / eligibility
Status Completed
Enrollment 44
Est. completion date November 2014
Est. primary completion date November 2014
Accepts healthy volunteers No
Gender Female
Age group 50 Years and older
Eligibility Inclusion Criteria:

- = 50 years ASA class I-II female who received surgery with endotracheal intubation

Exclusion Criteria:

- emergency surgery electrocardiography abnormality diabetes mellitus end stage renal disease moderate to severe cardiac disease moderate to severe liver dysfunction

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Intervention

Drug:
• Remifentanil
The effect site concentration of remifentanil

Locations
Country Name City State
Korea, Republic of Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine Seoul

Sponsors (1)
Lead Sponsor Collaborator
Severance Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome
Type Measure Description Time frame Safety issue
Primary The effect site concentration of remifentanil for preventing QTc interval prolongation 2 min Yes
See also
  Status Clinical Trial Phase
Completed NCT04994652 - Video- Or Direct Laryngoscopy for Endotracheal Intubation in Newborns N/A
Completed NCT03301324 - Intubation Assist Clinical Study N/A
Not yet recruiting NCT05534451 - Comparison Among Three Different Video Scope Guided Nasotracheal Intubation. N/A
Not yet recruiting NCT04116333 - Effect of Using Endotracheal Tube Introducer for Intubation During Mechanical Chest Compressions in a Manikin N/A
Recruiting NCT02001285 - Effect-site Concentration of Remifentanil for Blunting Hemodynamic Responses to Double-lumen Endobronchial Intubation N/A
Completed NCT02034643 - Transesophageal Echocardiography(TEE) Probe Insertion and Tracheal Cuff Pressure N/A
Completed NCT01718561 - The Difficult Airway Management Trial: "The DIFFICAIR-Trial" N/A
Completed NCT01227486 - Verification of Endotracheal Tube Placement by Ultrasound in the Obese Patient N/A
Withdrawn NCT01252173 - Measurement Of Endotracheal Tube Cuff Pressure In Emergency Department Patients N/A
Completed NCT04591769 - Tracheal Tube Cuff Shape and Pressure N/A
Completed NCT03841890 - The Clarus Video System and Direct Laryngoscope for Rapid Sequence Induction Intubation With Cricoid Pressure N/A
Recruiting NCT03716713 - CeraShield™ Endotracheal Tube Feasibility Study N/A
Not yet recruiting NCT03938506 - The Assessment of the Pilot Balloon Palpation Method in Different-sized Endotracheal Tubes
Not yet recruiting NCT01974505 - Learning Curve of Optiscope by Anesthesia Providers N/A
Completed NCT06107998 - Comparison of Different Methods for Determining Endotracheal Cuff Pressure N/A
Completed NCT02822846 - Evaluation of the Ability to Diagnose the Position of the Intubation Probe Thanks to Lung Ultrasonography
Completed NCT03116373 - Impact of Tracheal Tube Fixing Site on Its Mobility During Head Mobilization N/A
Completed NCT02423317 - Comparison of Miller's Blade and Airtraq Laryngoscope in Children N/A
Not yet recruiting NCT04872881 - Comparison of Effectiveness of Different Airway Management Methods During Percutaneous Tracheostomy Phase 4
Completed NCT04863846 - Evidence-based Algorithm for the Expected Difficult Intubation