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Insulin Resistance clinical trials

View clinical trials related to Insulin Resistance.

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NCT ID: NCT06266598 Completed - Insulin Resistance Clinical Trials

Effectiveness of Antidiabetic Treatment Applied in Childhood Obesity

Start date: November 17, 2019
Phase: Phase 4
Study type: Interventional

In our study, there are 33 healthy children with normal weight (control group) and 52 obese children who will be treated with metformin. To observe the efficacy of the 3-month treatment before and after metformin treatment, Zn, Zinc α-2 Glycoprotein (ZAG), Peroxisome proliferation activating receptor γ (PPARγ), Leptin (LEP) and Adiponectin (ADIPO) levels were compared, as well as anthropometric measurements and routine biochemistry tests.

NCT ID: NCT06240663 Completed - Insulin Resistance Clinical Trials

Walking Before or After Breakfast - Which is Better to Improve Health in Overweight Individuals?

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effectiveness of a home-based walking-based exercise intervention undertaken in the fed or fasted state to improve glycaemic control in overweight and obese individuals. This study will evaluate the adherence and compliance to this "real-world" exercise programme that requires no face-to-face contact with the research team. It is also hypothesised that individuals who exercise before breakfast (fasted) will see greater improvements in glycaemic control than those who exercise after breakfast.

NCT ID: NCT06237244 Completed - Clinical trials for Coronary Artery Disease

Insulin Resistance Indices and Coronary Artery Disease

Start date: December 1, 2018
Phase:
Study type: Observational [Patient Registry]

In this retrospective study from professor Kojuri clinic registry, total number of 1017 patients with first angiography were included and all data were recorded from registry. Insulin resistance was calculated using laboratory data

NCT ID: NCT06217679 Completed - Insulin Sensitivity Clinical Trials

Comparing the Effects of Different Types of Exercise on Glucose Handling

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

The purpose of the proposed study is to compare the acute effects of different types of exercise modalities on glucose handling in young, healthy males and females. The exercise modalities that will be compared include: a high intensity interval exercise (HIIE) protocol, a moderate intensity continuous exercise (MICE) protocol and a low-load, high-repetition (LL-HR) resistance exercise protocol.

NCT ID: NCT06092060 Completed - Insulin Resistance Clinical Trials

The Effect of a Multistrain Probiotic on Metformin Tolerance and Efficacy With Microbiota and Stool Metabolome in Insulin-resistant Women - a 12-week Randomized, Placebo-controlled, Double-blind Study

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The goal of this study is to evaluate the efficacy of metformin on insulin sensitivity and vascular endothelial function with respect to gut microbiota and metabolome in women with established insulin resistance and its tolerance after 12 weeks of probiotic therapy. The hypothesis is probiotic therapy in women with established insulin resistance undergoing metformin treatment increases the drug's efficacy to improve insulin sensitivity and intestinal endothelial function, and reduces gastrointestinal side effects. Study participants will be randomly assigned to 2 groups, taking a probiotic (GS) or a placebo (GP). The randomization scheme will be computer-generated using permuted blocks of block size 4.

NCT ID: NCT06031753 Completed - Insulin Resistance Clinical Trials

Effects of Intermittent Fasting on Polycystic Ovary Syndrome (PCOS) Compared to Standard Treatment

Start date: June 3, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effects of Time restricted eating in patients diagnosed with polycystic ovary syndrome, comparing it to the standard hormonal treatment.

NCT ID: NCT05957120 Completed - Inflammation Clinical Trials

Subclinical Impairment of Cardiovascular System in Patients With Psoriasis

PaS
Start date: January 3, 2022
Phase:
Study type: Observational

A cross-sectional study will be conducted, which will include 80 young patients with psoriasis, aged 30-45 years, treated with five different types of antipsoriatic treatment, and 20 healthy patients. All 100 subjects will be subjected to anthropometric measurements, blood will be collected for laboratory tests, and an imaging test will be performed to determine the function of the endothelium and arterial stiffness. The results will then be statistically analyzed.

NCT ID: NCT05951309 Completed - Insulin Resistance Clinical Trials

Myoinositol Treatment and Asprosin Levels in PCOS

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Policystic ovary syndrome is the most common endocrinopthy during reproductive period. One of the factors implicated in the pathogenesis is insulin resistance. Asprosin, which is secreted from white adipose tissue is a new candidate for insulin resistance. Myoinositol is known to reduce insulin resistance in PCOS patients. The effect of myoinsitol on serum asprosin levels is unknown yet. This study aimed to evaluate the effect of myoinositol on serum asprosin levels in PCOS patients.

NCT ID: NCT05904509 Completed - Atopic Dermatitis Clinical Trials

Insulin Resistance in Atopic Dermatitis Patients

Start date: September 1, 2022
Phase:
Study type: Observational

The aim of the study is to determine the relationship between insulin resistance and disease duration and severity of atopic dermatitis.

NCT ID: NCT05902546 Completed - Diabetes Mellitus Clinical Trials

Effect of HIIT Vs Moderate Intensity Aerobic Exercise on Insulin Resistance in Type 2 DM

Start date: January 7, 2023
Phase: N/A
Study type: Interventional

Comparing between the efficacy of high intensity interval training and moderate intensity aerobic exercises on insulin resistance in type 2 Diabetes Mellitus.