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Pilot Study to Validate ex Vivo Expression of Specific Biomarkers of Human Resolutive Macrophages — RESOMACRO  

Inflammation Clinical Trial

Official title:
Pilot Study to Validate ex Vivo Expression of Specific Biomarkers of Human Resolutive Macrophages

Clinical Trial Summary

Human resolutive macrophages are essential immune cells in the resolution of inflammation. This particular type of macrophages remains poorly known and currently there are no biomarkers to identify them in vivo. Within UMR1098-RIGHT, specific biomarkers (secreted molecules and membrane receptors) of human resolutive macrophages (healthy volunteers) have been identified in vitro, but their existence in vivo remains an outstanding issue. An exploratory study (lack of data from the literature) will validate the ex vivo expression of these markers in samples of patients whose inflammation is not, or little, supported by the available therapies (NSAIDs, biotherapies, corticosteroids).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05106075
Study type Interventional
Source Centre Hospitalier Universitaire de Besancon
Contact Thomas CHERRIER, MCU-PH
Phone +33(0)768207057
Email tcherrier@unistra.fr
Status Recruiting
Phase N/A
Start date July 7, 2021
Completion date January 7, 2024
View Details
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