Inflammation Clinical Trial
Official title:
Evaluation of the Effects of a Daily Dose of 5 mg of Tadalafil on Lymphocyte to Monocyte Ratio and Monocyte to High-Density Lipoprotein Ratio in Patients With Erectile Dysfunction
The aim of the study was to investigate whether daily 5 mg tadalafil over eight weeks affects
to Lymphocyte/Monocyte ratio (LMR) and Monocyte/High-Density Lipoprotein ratio (MHR) in
patients with erectile dysfunction (ED).
Thirty-one patients with organic ED and 31 healthy controls between July 2017 and November
2018 were included in this retrospective study. To avoid bias, the patients were randomly
selected and the controls were also incorporated consecutively. The presence of ED was
determined according to the International Erectile Function Index-5 (IIEF-5). The patients
and the controls were evaluated in terms of IIEF-5, complete blood count, serum biochemistry,
LMR, and MHR.
The medical records of the heterosexual men treated with the diagnosis of organic ED in the
Urology department of a private hospital between July 2017 and October 2018 were evaluated
retrospectively. The number of samples to be included in the study was determined by the help
of the computer-assisted power analysis. Random sampling was performed from all cohorts of
patients with ED. Thirty-one male patients between the ages of 39-65 with organic erectile
dysfunction more than one year and treated with OAD 5 mg dose of tadalafil for eight weeks
were selected as the treatment group (group T)The patients in group T have been assessed both
before (T1) and after (T2) the treatment.
Between the ages of 39-65, thirty-one healthy men who were admitted to the internal medicine
outpatient clinic for their annual follow-up were selected consecutively and the control
group (group C) was formed. All subjects in the control group were sexually active men with
regular monogamous heterosexual relationships during the last one year.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT03995979 -
Inflammation and Protein Restriction
|
N/A | |
| Completed |
NCT03255187 -
Effect of Dietary Supplemental Fish Oil in Alleviating Health Hazards Associated With Air Pollution
|
N/A | |
| Completed |
NCT04507867 -
Effect of a NSS to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III
|
N/A | |
| Completed |
NCT03577223 -
Egg Effects on the Immunomodulatory Properties of HDL
|
N/A | |
| Completed |
NCT04383561 -
Relationship Between LRG and Periodontal Disease
|
N/A | |
| Active, not recruiting |
NCT03622632 -
Pilot Study to Measure Uric Acid in Traumatized Patients: Determinants and Prognostic Association
|
||
| Completed |
NCT06216015 -
Exercise Training and Kidney Transplantation
|
N/A | |
| Completed |
NCT04856748 -
Nomogram to Diagnose Prostatic Inflammation (PIN) in Men With Lower Urinary Tract Symptoms
|
||
| Completed |
NCT05529693 -
Efficacy of a Probiotic Strain on Level of Markers of Inflammation in an Elderly Population
|
N/A | |
| Recruiting |
NCT05415397 -
Treating Immuno-metabolic Depression With Anti-inflammatory Drugs
|
Phase 3 | |
| Recruiting |
NCT05670301 -
Flemish Joint Effort for Biomarker pRofiling in Inflammatory Systemic Diseases
|
N/A | |
| Recruiting |
NCT04543877 -
WHNRC (Western Human Nutrition Research Center) Fiber Intervention Study
|
Early Phase 1 | |
| Recruiting |
NCT05775731 -
Markers of Inflammation and of the Pro-thrombotic State in Hospital Shift and Day Workers
|
||
| Completed |
NCT03859934 -
Metabolic Effects of Melatonin Treatment
|
Phase 1 | |
| Completed |
NCT03429920 -
Effect of Fermented Soy Based Product on Cardiometabolic Risk Factors
|
N/A | |
| Completed |
NCT06065241 -
Quantifiably Determine if the Botanical Formulation, LLP-01, Has a Significant Clinical Effect on Proteomic Inflammatory Biomarkers and Epigenetic Changes in Healthy, Older Individuals.
|
N/A | |
| Active, not recruiting |
NCT05864352 -
The Role of Dietary Titanium Dioxide on the Human Gut Microbiome and Health
|
||
| Completed |
NCT03318731 -
Efficacy and Safety of Fenugreek Extract on Markers of Muscle Damage and Inflammation in Untrained Males
|
N/A | |
| Not yet recruiting |
NCT06134076 -
Comparing Effects of Fermented and Unfermented Pulses and Gut Microbiota
|
N/A | |
| Not yet recruiting |
NCT05910489 -
Micro and Nanoplastics in Greenhouse Workers: Biomarkers of Exposure and Effect
|