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Clinical Trial Summary

• Correlation of a glycoprotein panel with prostate biopsy outcome and PCa aggressiveness


Clinical Trial Description

The main objective of this study is to correlate a glycoprotein panel with prostate biopsy outcome, i.e. distinguishing PCa from benign prostatic conditions as well as high-grade cancer. The quantities of the two protein analytes cathepsin D (CTSD) and thrombospondin 1 (THBS1) are measured in human serum samples. In combination with percent free PSA (%fPSA), the results are correlated with prostate biopsy outcome. The potential future benefit of using this glycoprotein panel is to validate positive tPSA tests in men with negative digital rectal examination (DRE) and enlarged prostates to reduce the need for undergoing a biopsy, thereby reducing unnecessary biopsies and potentially predicting high-grade disease. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03565289
Study type Observational
Source ProteoMediX AG
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Status Completed
Phase
Start date August 14, 2018
Completion date January 31, 2020