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Immune System Disorders clinical trials

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NCT ID: NCT03351543 Completed - Clinical trials for Immune System Disorders

Effect of Microbial Exposure on Health, Particularly Immune System

ADELEWP1t4
Start date: March 2016
Phase: Phase 1
Study type: Interventional

The effect of microbial exposure on healthy human subjects will be investigated. Changes in cytokine and IgE and vaccine response will be measured. The hypothesis is that microbial exposure increases the measured responses.

NCT ID: NCT01002742 Completed - Clinical trials for Graft-versus-Host Disease

Acute Graft-versus-Host Disease Treatment (BMT CTN 0802)

Start date: January 2010
Phase: Phase 3
Study type: Interventional

The study is a Phase III, randomized double blind, placebo controlled, and trial evaluating the addition of Mycophenolate mofetil (MMF) vs. placebo to systemic corticosteroids as initial therapy for acute Graft Vs Host Disease (GVHD). The primary endpoint will be GVHD free survival at Day 56 post randomization.

NCT ID: NCT00224874 Completed - Clinical trials for Graft vs Host Disease

Treatment for Acute Graft-Versus-Host Disease (BMT CTN 0302)

Start date: September 2005
Phase: Phase 2
Study type: Interventional

The study is a randomized Phase II, four arm treatment trial. The primary purpose of the study is to define new agents with promising activity against acute graft-versus-host disease (GVHD) suitable for testing against corticosteroids alone in a subsequent Phase III trial.