Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to to evaluate the safety and efficacy of hyperbaric oxygen in term gestation newborn infants with hypoxic-ischemic encephalopathy..


Clinical Trial Description

Hypoxic-ischemic encephalopathy (HIE) remains a major cause of neonatal death and long term disabilities. Data from animal studies have shown protective effects of hyperbaric oxygen therapy to impaired brain. Recently research priorities have moved from bench to bedside. Several studies have shown a trend for brain protection of hyperbaric oxygen therapy has emerged as a promising treatment for HIE. Therefore,the investigators organized a multi-centered randomized controlled trial of hyperbaric oxygen therapy in HIE newborn infants. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02894866
Study type Interventional
Source Nanfang Hospital of Southern Medical University
Contact Lishan Guo, Doctor
Phone +86 13580538496
Email nfyygls@163.com
Status Recruiting
Phase N/A
Start date October 2016
Completion date September 2021

See also
  Status Clinical Trial Phase
Recruiting NCT03024021 - Cerebral Oxymetry and Neurological Outcome in Therapeutic Hypothermia N/A
Active, not recruiting NCT01913340 - Neonatal Erythropoietin And Therapeutic Hypothermia Outcomes in Newborn Brain Injury (NEATO) Phase 1/Phase 2
Enrolling by invitation NCT02260271 - Florida Neonatal Neurologic Network
Terminated NCT01192776 - Optimizing (Longer, Deeper) Cooling for Neonatal Hypoxic-Ischemic Encephalopathy(HIE) Phase 3
Not yet recruiting NCT03123081 - Role of Umbilical Cord Milking in the Management of Hypoxic-ischemic Encephalopathy in Neonates N/A
Recruiting NCT03485781 - Propofol-induced EEG Changes in Hypoxic Brain Injury
Not yet recruiting NCT03681314 - Umbilical Cord Milking in Neonates Who Are Depressed at Birth-Developmental Follow Up (MIDAB-FU) N/A
Not yet recruiting NCT03682042 - Umbilical Cord Milking in Neonates With Hypoxic Ischemic Encephalopathy- Developmental Follow Up N/A
Not yet recruiting NCT03657394 - Umbilical Cord Milking in Neonates Who Are Depressed at Birth Phase 3
Enrolling by invitation NCT02264808 - Developmental Outcomes N/A
Recruiting NCT01793129 - Preemie Hypothermia for Neonatal Encephalopathy Phase 2/Phase 3
Completed NCT00890409 - Safety and Efficacy of Hypothermia to Treat Neonatal Hypoxic-Ischemic Encephalopathy Phase 3
Recruiting NCT03079167 - PAEAN - Erythropoietin for Hypoxic Ischaemic Encephalopathy in Newborns Phase 3
Recruiting NCT03246243 - Quantitative Assessment of Sucking for Early Diagnosis of Brain Injury in Infants at High Risk N/A
Completed NCT02529202 - Dexmedetomidine Pharmacokinetics in Neonates During Therapeutic Hypothermia Phase 0
Completed NCT01059461 - Study of Cerebrolysin for Treatment of Infants With History of Neonatal Hypoxic Ischemic Encephalopathy Phase 2
Completed NCT03079284 - Holding, Stress, and Bonding During Therapeutic Hypothermia N/A
Recruiting NCT03181646 - Role of Citicoline in Treatment of Newborns With Hypoxic Ischemic Encephalopathy Phase 3
Not yet recruiting NCT03079492 - MRI of Neonate With HIE Before and During the Moderate Hypothermia N/A
Completed NCT00817401 - Systemic Hypothermia Improves Outcome of Hypoxic-Ischemic Encephalopathy Phase 1/Phase 2