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Clinical Trial Summary

This is the report to assess the effect of supplementation with soybean peptides on blood pressure among people with mild hypertension. Overall, soybean peptides consumption for 8 weeks could successfully reduce mean diastolic and systolic BP through the suppression of ACE that is linked to downstream suppresion of angiotensin II formation, which further decreases the sympathetic outflow that leads to hypertension.


Clinical Trial Description

This is the report to assess the effect of supplementation with soybean peptides on blood pressure among people with mild hypertension. Thirty subjects with systolic blood pressure (SBP) between 120 and 159 mm Hg and/or diastolic blood pressure (DBP) between 80 and 99 mm Hg were randomized to ingest 2 bags soybean peptides or placebo perday for 8 weeks of a stage. Anthropometric measurements (blood pressure, body weight, body fat) and blood biochemical markers including fasting blood glucose (FBG), albumin, total cholesterol (TC), triglyceride (TG), HDL-C, LDL-C, creatinine (Cr), blood urea nitrogen (BUN), AST, ALT were examined every four weeks. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03828955
Study type Interventional
Source Chung Shan Medical University
Contact
Status Completed
Phase N/A
Start date March 2016
Completion date January 2017

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