Hypertension Clinical Trial
Official title:
Effects of Multidisciplinary Intensive Targeted Care in Improving Diabetes Outcomes: a Randomized Controlled Pilot Study - the Integrated Diabetes Education, Awareness and Lifestyle Modification in Singapore (IDEALS) Program
This study aims to investigate whether channeling purposefully structured resources to patients at high risk of developing diabetic complications to interdisciplinary team clinic consultations, interspersed with closer remote follow-up and aided by simple technology will be more effective than usual care in controlling diabetes mellitus, controlling multiple cardiovascular risk factors and reducing clinical event rates.
The prevalence of diabetes in Singapore is estimated to grow from 400,000 to 670,000 by 2030
and an alarming one million by 2050 with the continuing rise in obesity prevalence. The
current system currently has no formal stratification of patients for channelling of
structured resources to patients that require more intensive treatment and follow-up (those
at higher risk of progressing to having complications from diabetes due to poor glycemic
control, or those who have signs of early complications).
We will therefore be researching effective health system delivery strategies to improve
achievement of treatment targets (eg. HbA1c, blood pressure, LDL) and reduce vascular
complications of diabetes mellitus (retinopathy, proteinuria, end stage renal disease,
ischemic heart disease). These include:
- Stratification and channelling purposefully structured resources to patients with poorly
controlled diabetes mellitus defined as having an HbA1c >9% on 2 or more occasions, and
patients with diabetic complications (estimated glomerular filtration rate eGFR
30-60ml/min or proteinuria >0.5g/day or urine microalbumin:creatinine ratio >300mg/g)
- Training of all doctors/DNEs/dietitians involved in the counselling of patients in the
field of motivational interviewing
- Providing easy accessibility to resources to allow patients to self-monitor their
capillary blood glucose and blood pressure in between clinic visits - loaning of blood
pressure units and glucometers for short (1-2 week) periods regularly
- Providing frequent telephone counselling by DNEs and Renal Pharmacists with regards to
titration of medications, in particular ACE-inhibitors or angiotensin-receptor blockers
to reach treatment targets
- Utilisation of social media and smart phone/tablet applications for relevant patients to
improve and increase patient-healthcare professional interaction with regards to
diabetes, provide daily bite-sized education via tablet/smart phone media/social media
and improve compliance to exercise targets
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT04591808 -
Efficacy and Safety of Atorvastatin + Perindopril Fixed-Dose Combination S05167 in Adult Patients With Arterial Hypertension and Dyslipidemia
|
Phase 3 | |
| Recruiting |
NCT04515303 -
Digital Intervention Participation in DASH
|
||
| Completed |
NCT05433233 -
Effects of Lifestyle Walking on Blood Pressure in Older Adults With Hypertension
|
N/A | |
| Completed |
NCT05491642 -
A Study in Male and Female Participants (After Menopause) With Mild to Moderate High Blood Pressure to Learn How Safe the Study Treatment BAY3283142 is, How it Affects the Body and How it Moves Into, Through and Out of the Body After Taking Single and Multiple Doses
|
Phase 1 | |
| Completed |
NCT03093532 -
A Hypertension Emergency Department Intervention Aimed at Decreasing Disparities
|
N/A | |
| Completed |
NCT04507867 -
Effect of a NSS to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III
|
N/A | |
| Recruiting |
NCT05529147 -
The Effects of Medication Induced Blood Pressure Reduction on Cerebral Hemodynamics in Hypertensive Frail Elderly
|
||
| Recruiting |
NCT06363097 -
Urinary Uromodulin, Dietary Sodium Intake and Ambulatory Blood Pressure in Patients With Chronic Kidney Disease
|
||
| Recruiting |
NCT05976230 -
Special Drug Use Surveillance of Entresto Tablets (Hypertension)
|
||
| Completed |
NCT06008015 -
A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1015" and Co-administration of "BR1015-1" and "BR1015-2" Under Fed Conditions in Healthy Volunteers
|
Phase 1 | |
| Completed |
NCT05387174 -
Nursing Intervention in Two Risk Factors of the Metabolic Syndrome and Quality of Life in the Climacteric Period
|
N/A | |
| Completed |
NCT04082585 -
Total Health Improvement Program Research Project
|
||
| Recruiting |
NCT05121337 -
Groceries for Black Residents of Boston to Stop Hypertension Among Adults Without Treated Hypertension
|
N/A | |
| Withdrawn |
NCT04922424 -
Mechanisms and Interventions to Address Cardiovascular Risk of Gender-affirming Hormone Therapy in Trans Men
|
Phase 1 | |
| Active, not recruiting |
NCT05062161 -
Sleep Duration and Blood Pressure During Sleep
|
N/A | |
| Completed |
NCT05087290 -
LOnger-term Effects of COVID-19 INfection on Blood Vessels And Blood pRessure (LOCHINVAR)
|
||
| Not yet recruiting |
NCT05038774 -
Educational Intervention for Hypertension Management
|
N/A | |
| Completed |
NCT05621694 -
Exploring Oxytocin Response to Meditative Movement
|
N/A | |
| Completed |
NCT05688917 -
Green Coffee Effect on Metabolic Syndrome
|
N/A | |
| Recruiting |
NCT05575453 -
OPTIMA-BP: Empowering PaTients in MAnaging Blood Pressure
|
N/A |