Human Papillomavirus Viruses Clinical Trial
Official title:
Epidémiologie de l'Infection à Human Papilloma Virus Chez Les Femmes Vivant Sur Les Fleuves Maroni et Oyapock
Cervical cancer is the second most frequent cancer of women in French Guiana. Studies have
shown that populations living in remote villages in the interior of the territory have early
sexual relations and that multiple sexual partnerships are frequent. Hence, the main
objective of the study was to determine the prevalence of HPV in these areas, and the
predictive factors and epidemiology of this viral infection.
Methods - This multicentric cross sectional study aimed the population of women aged 20 to
65 years, living in the remote villages along the Maroni and Oyapock rivers. Women wishing
to participate will be included after being informed of the study team schedule through
radio address and key opinion leaders. The search for HPV and cytologic examinations will be
performed for each woman. 2 samples will be taken from each woman: one sample will be sent
to Fort De France hospital for cytology, and HPV testing; cytologic analyses will be
performed using the 2001 Bethesda classification. Another sample will be sent to Pasteur
Institute in Cayenne for sequencing and detection of E6 and E7 RNA which are associated with
carcinogenesis. HPV infection will be defined by the detection of viral DNA using the
GREINER-BIO-ONE kit. Statistical analysis of the results will use STATA software and mapping
will use Mapinfo.
n/a
Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05884697 -
Let's K-Talk - HPV Study for Ethnic Koreans
|
N/A | |
| Not yet recruiting |
NCT06223568 -
Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer
|
Phase 2 |