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Mebendazole Study Against Hookworm Infections in Children and Adolescents in Ghana

Hookworm Infections Clinical Trial

Official title:
Efficacy and Safety of a Single-dose Regimen and a Multi-dose Regimen of Mebendazole Against Hookworm Infections in Children and Adolescents in Ghana: a Randomized Controlled Trial

Clinical Trial Summary

The Ghana study will hypothesize that both the multiple dose and single dose of mebendazole will achieve effective cure rates against hookworm among children and adolescents. This study is intended to be a pilot study for a planned Phase 3 registration trial of a new drug for hookworm, tribendimidine.

Clinical Trial Description

This study will determine the Cure Rates (CRs) of mebendazole regimens to be used as comparator drug regimens in the future pivotal trial of tribendimidine and will provide evidence of the efficacy and safety of mebendazole among children and adolescents infected with hookworm in Ghana. Children and adolescents bear a large burden of morbidity from hookworm infection, so building the evidence base for effective treatments in this population has important public health implications in Ghana and other endemic settings. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03261596
Study type Interventional
Source PATH
Contact
Status Withdrawn
Phase Phase 4
Start date September 2017
Completion date December 2017
View Details
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