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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03579381
Other study ID # AHF 03
Secondary ID
Status Completed
Phase
First received
Last updated
Start date July 31, 2017
Est. completion date January 25, 2019

Study information

Verified date January 2021
Source AIDS Healthcare Foundation
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Specimen Repository for HIV Immunopathogenesis Studies


Description:

The goal is to build a large specimen repository for collaborating scientists to run studies of immunity and HIV-1.


Recruitment information / eligibility

Status Completed
Enrollment 9
Est. completion date January 25, 2019
Est. primary completion date January 25, 2019
Accepts healthy volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: 1. HIV positive (acutely infected, viremic and elite controllers) 2. Signed Informed Consent Form 3. Age at least 18 years old 4. Immune controllers, two types: "Elite suppressors" (HIV-positive with any three consecutive plasma HIV-1 RNA PCR undetectable while off treatment) or "viremic suppressors" (HIV-positive with any three consecutive HIV-1 RNA PCR <3000 while off treatment). 5. Acutely infected subjects: Persons identified to have a negative HIV antibody response (ELISA) but positive detection of HIV-1 in the blood (RT-PCR) or individuals who have evidence of a recent (past 30 days) HIV negative result along with a current HIV positive result. Exclusion Criteria: 1. Uncontrolled bleeding diathesis. 2. Pregnant. 3. Inability to provide informed consent.

Study Design


Locations

Country Name City State
United States AIDS Healthcare Foundation - Public Health Division Los Angeles California

Sponsors (2)

Lead Sponsor Collaborator
AIDS Healthcare Foundation University of California, Los Angeles

Country where clinical trial is conducted

United States, 

Outcome

Type Measure Description Time frame Safety issue
Primary HIV progression from acute infection to viral suppression Outcomes will depend on scientists who use the samples for further study 2 years
Primary HIV progression and control by elite and viremic suppressors Outcomes will depend on scientists who use the samples for study 2 years
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