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Clinical Trial Summary

The purpose of the study is to identify molecular markers at the level of molecular pathway activation to predict efficacy of anti-HER2 therapy with Trastuzumab.


Clinical Trial Description

Biopsy and/or surgical samples from Her2-positive breast cancer patients treated with Trastuzumab alone or in combinations with other regimens of chemotherapy with known clinical outcomes will be collected and subjected to mRNA sequencing. Expression profiles will be analysed using original bioinformatic platform Oncobox. Based on comparison of molecular pathways activation strength and clinical response to Trastuzumab and chemotherapy, this study aims to identify molecular markers predicting efficacy of therapy with Trastuzumab and the possibility of further relapse. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03521245
Study type Observational
Source OmicsWay Corp.
Contact
Status Active, not recruiting
Phase
Start date October 1, 2017
Completion date May 1, 2022

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