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Clinical Trial Summary

RAISE is a multicenter randomized controlled trial to assess the efficacy of adjuvant radiotherapy for controlling postsurgical recurrence in HCC patients with narrow margin (≤ 1 cm) after curative resection.


Clinical Trial Description

RAISE trial will recruit 148 patients, and they will be randomized (1:1) to two groups (the surgery group and the surgery-radiotherapy group). Random assignment was stratified by the condition of MVI and tumor size. All patients in the surgery-radiotherapy group received Intensity Modulated Radiation Therapy (IMRT) within 1-3 months after surgical resection. The prescription dose was planned at 50 gray in 25 fractions over 5-6 weeks. The trial is to verify whether adjuvant radiotherapy prolongs recurrence-free survival in patients with a narrow resection margin. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03732105
Study type Interventional
Source Sun Yat-sen University
Contact Ming Kuang, PhD
Phone 008687755766
Email kuangm@mail.sysu.edu.cn
Status Recruiting
Phase N/A
Start date March 6, 2019
Completion date August 11, 2025

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