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Clinical Trial Summary

Patients with high clinical suspicion of hepatobiliary malignancies should undergo PET/CT examination with two imaging agents, 68Ga-FAPI (fibroblast activation protein inhibitor) and 18F-FDG within one week, and collect tumor tissue. Finally, the PET/CT results were compared with the pathology report to evaluate the role of 68Ga-FAPI PET/CT imaging in the diagnosis of hepatobiliary malignancies


Clinical Trial Description

Patients with high clinical suspicion of hepatobiliary malignancies should undergo PET/CT examination with two imaging agents, 68Ga-FAPI (fibroblast activation protein inhibitor) and 18F-FDG within one week. After comprehensive clinical evaluation, if the patient can be treated with surgery, surgery will be performed, and the patient's pathological specimens will be collected after surgery ; If the patient has no possibility of surgery, ultrasound-guided needle biopsy is performed, and biopsy specimens are collected. Finally, the PET/CT results were compared with the pathology report to evaluate the application value of 68Ga-FAPI PET/CT imaging in the diagnosis and staging of hepatobiliary malignant tumors, and to analyze the guiding significance for the treatment decision of hepatobiliary malignant tumors. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05264688
Study type Observational
Source Zhongnan Hospital
Contact Yufeng Yuan
Phone 13995564795
Email yuanyf1971@whu.edu.cn
Status Recruiting
Phase
Start date January 20, 2022
Completion date October 31, 2022

See also
  Status Clinical Trial Phase
Terminated NCT01200082 - Sulfation of Bile Acids as a Biomarker for Hepatobiliary Diseases