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Clinical Trial Summary

Registry participants with advanced malignancy or myelodysplasia will have a sample of their tumor or tissue analysed for genetic alterations using next generation sequencing (NGS) performed in a lab that has been certified to meet a high quality standard. Treatments and outcomes will be reported to the registry to allow further understanding of how genetic differences can lead to better diagnosis and treatments.


Clinical Trial Description

Every malignancy or myelodysplasia is different on a molecular (genetic) level even in patients with the same diagnosis. These differences often give prognostic information, determine what types of treatments are available for a patient, as well as determine outcomes. In this registry, the method of identifying the genetic difference of the disease (using Next Generation Sequencing or NGS) is standardized, the treatments received by a patient, and the outcome of these treatments are entered into a database where all identifying information is removed.

Payers (insurance companies) or others will generally pay for the testing, laboratories will report the genetic information, physicians and eventually patients will report treatments and outcomes. This information will then be reviewed frequently and analyzed to find better methods to improve the testing or treatments of disease.

It is expected that dozens of other trials or registries will eventually be available for participants. ;


Study Design


Related Conditions & MeSH terms

  • Anal Neoplasms
  • Anus Neoplasms
  • Biliary Tract Neoplasms
  • Bladder Neoplasms
  • Brain Neoplasms
  • Breast Neoplasms
  • Colon Neoplasms
  • Colonic Neoplasms
  • Endometrial Neoplasms
  • Gastric Neoplasms
  • Head and Neck Neoplasms
  • Hematologic Neoplasms
  • Kidney Neoplasms
  • Liver Neoplasms
  • Lung Neoplasms
  • Melanoma
  • Multiple Myeloma
  • Myelodysplastic Syndromes
  • Neoplasms
  • Ovarian Neoplasms
  • Pancreatic Neoplasms
  • Preleukemia
  • Prostate Neoplasms
  • Prostatic Neoplasms
  • Rectal Neoplasms
  • Sarcoma
  • Skin Neoplasms
  • Stomach Neoplasms
  • Testicular Neoplasms
  • Urinary Bladder Neoplasms
  • Uterine Cervical Neoplasms

NCT number NCT02900248
Study type Observational [Patient Registry]
Source CureOne
Contact
Status Terminated
Phase
Start date October 2, 2017
Completion date March 29, 2019

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