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L-Arginine Supplementation and Exercise; L-Arginine Supplementation and Renal Function

Heart Transplantation Clinical Trial

Official title:
Effects of Oral Chronic L-Arginine Supplementation on Exercise and Renal Function of Heart Transplant Recipients

Clinical Trial Summary

- exercise capacities are still altered after heart transplantation partly due to peripheral endothelial dysfunction

- cyclosporin-induced renal dysfunction may be due to renal endothelial dysfunction and can be reversed in an animal model by L-arginine supplementation

- to determine the potential beneficial effect of L-arginine supplementation on exercise capacity and renal function of heart transplant recipients

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00213915
Study type Interventional
Source University Hospital, Strasbourg, France
Contact
Status Completed
Phase Phase 4
Start date February 2004
Completion date December 2004
View Details
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