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Heart Failure clinical trials

View clinical trials related to Heart Failure.

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NCT ID: NCT03241069 Completed - Acute Heart Failure Clinical Trials

Dynamic Variation of Impedance Cardiography(DYVIC) as a Diagnostic Tool of Acute Heart Failure (AHF)

DYVIC
Start date: July 2012
Phase: N/A
Study type: Interventional

Dynamic variations of bio-impedance measured cardiac output using pharmacologic (inhaled nitrate) and non pharmacologic intervention (sitting position, passive leg rising and valsalva maneuver) could be used to detect acute heart failure in patients admitted to the ED for dyspnea.

NCT ID: NCT03240237 Not yet recruiting - Clinical trials for Heart Failure, Diastolic

CCM in Heart Failure With Preserved Ejection Fraction

Start date: August 15, 2017
Phase: N/A
Study type: Interventional

This pilot study will evaluate the efficacy and safety of CCM therapy in heart failure patients with baseline EF≥50% (HFpEF) who have New York Heart Association (NYHA) Class II or III symptoms despite appropriate medication. The terminology of the HF classification HFpEF is based on the 2016 European Society of Cardiology (ESC) Heart Failure Guidelines.

NCT ID: NCT03238937 Not yet recruiting - Heart Failure Clinical Trials

Phrenic Nerve Stimulation for Treatment of Central Sleep Apnea

STIMULATE-CSA
Start date: August 10, 2017
Phase: N/A
Study type: Interventional

The study objectives are to demonstrate the ease and safety of bilateral cervically implanted phrenic nerve stimulators for Central Sleep Apnea in patients with Heart Failure. To demonstrate the efficacy, both in the short and long term, of implanted phrenic nerve stimulators in patients with Central Sleep Apnea and Heart Failure. Central Sleep Apnea is a form of hypoventilation syndrome, for which this device is FDA approved. We will also determine if the patient's quality and duration of life is improved by using the PNS to treat CSA in heart failure patients.

NCT ID: NCT03238729 Not yet recruiting - Heart Failure Clinical Trials

Proof-of-Concept Study of Heart Habits Application for Patients With Heart Failure

Start date: August 2017
Phase: N/A
Study type: Interventional

This study assesses the ability of ambulatory patients with heart failure (HF) to use a smartphone application created for the management of patients with chronic HF. This study will aim: - To understand the frequency with which ambulatory HF patients engage with this smartphone application. - To determine whether patient's knowledge of HF and its management has improved with the use of this smartphone application. - To assess improvement in quality of life measures related to the use of this smartphone application. - To assess improvement in lifestyle measures related to the use of this smartphone application.

NCT ID: NCT03238690 Recruiting - Heart Failure Clinical Trials

LVAD Conditioning for Cardiac Recovery

Start date: June 23, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the potential recovery of heart function in end-stage heart failure patients supported with a Left Ventricular Assist Device (LVAD) through applying a myocardial conditioning protocol. During myocardial conditioning, LVAD speed is reduced gradually in order to increase the work load of the heart. Multiple previous studies have shown that interventions like this may improve heart function and give patients the opportunity for a better quality of life.

NCT ID: NCT03237923 Recruiting - Clinical trials for Congestive Heart Failure

Evaluation of the EasySense System in Congestive Heart Failure

Start date: July 1, 2017
Phase: N/A
Study type: Observational

The EasySense device is a non-invasive device designed to measure lung fluid in patients with Congestive Heart Failure (CHF). This study seeks to evaluate the efficacy of the EasySense system in measuring lung fluid volume.

NCT ID: NCT03237858 Not yet recruiting - Clinical trials for Heart Failure, Congestive

Multiple Cardiac Sensors for the Management of Heart Failure

MANAGE-HF
Start date: September 2017
Phase: N/A
Study type: Interventional

The MANAGE-HF study is a multi-center, global, prospective, open label, multi-phase trial intended to evaluate the clinical efficacy of the HeartLogic heart failure diagnostic feature.

NCT ID: NCT03235843 Recruiting - Heart Failure Clinical Trials

Rate Adaptive Atrial Pacing in Heart Failure

ADAPTION
Start date: August 1, 2017
Phase: N/A
Study type: Interventional

The ADAPTION trial is an investigator initiated prospective randomized doubleblind cross-over pilot study in a multi-center setting. Aim: to assess the ability of minute ventilation (MV) sensor driven rate adaptive atrial stimulation to restore functional capacity and quality of life in heart failure patients with chronotropic incompetence. Methods: heart failure patients (left ventricular ejection fraction ≤35% & New York Heart Assessment II or III) who were implanted with a 2-chamber implantable cardioverter defibrillator (ICD) device equipped with a MV sensor that are diagnosed with chronotropic incompetence will be included in the study. Patients will be randomized in a 1:1 fashion to rate responsive pacing (MV sensor only) function ON (AAIR mode) or OFF (DDI mode). After 3 months the pacing mode will be switched to the opposite mode.

NCT ID: NCT03235700 Recruiting - Clinical trials for Coronary Artery Disease

Hyperemic Efficacy of IV Adenosine in HFrEF

HF-FFR
Start date: March 1, 2017
Phase: N/A
Study type: Interventional

Little is known about the hyperemic efficacy of IV adenosine as well as safety in patients with heart failure with reduced ejection fraction (HFrEF) because they were excluded from the major FFR studies. We will evaluate the feasibility and hyperemic efficacy of IV adenosine in patients with HFrEF in comparison with IC nicorandil for invasive physiological assessment using a coronary pressure wire.

NCT ID: NCT03234647 Not yet recruiting - Acute Heart Failure Clinical Trials

First In Human Study of the Doraya Catheter for the Treatment of AHF Patients

Start date: November 2017
Phase: N/A
Study type: Interventional

Safety and performance evaluation of the Doraya catheter in patients admitted with AHF.