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Clinical Trial Summary

The purpose of the study is to evaluate whether the administration of iron to patients with heart failure and preserved ejection fraction results in an improvement of symptoms and functional class, in addition to evaluating whether oral iron is equivalent to intravenous iron to achieve this improvement.

Clinical Trial Description

Iron deficiency is one of the most prevalent co-morbid conditions in chronic heart failure. In the absence of any iron treatment, it is estimated that up to 50% of patients with heart failure have low levels of available iron. Treatment with intravenous iron improves exercise tolerance , quality of life , and reduces hospitalization in patients with chronic heart failure and reduced ejection fraction. However data on the effect of iron therapy in patients with heart failure with preserved ejection fraction are still lacking. The evidence related to oral iron therapy in HF is limited and no randomized trials compared oral iron vs no iron therapy in the absence of erythropoiesis-stimulating agents. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT03833336
Study type Interventional
Source Institut de Recerca Biomèdica de Lleida
Contact Jose Luis Morales-Rull, MD,PhD
Phone 0034+616424858
Status Recruiting
Phase Phase 3
Start date August 23, 2017
Completion date June 2020

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