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The Accuracy Of A Novel Platelet Activity Assay In Humans On Antiplatelet Agents: Pharmacodynamics And Comparison With Light Transmission Aggregometry

Healthy Clinical Trial

Official title:
The Accuracy Of A Novel Platelet Activity Assay In Humans On Antiplatelet Agents: Pharmacodynamics And Comparison With Light Transmission Aggregometry

Clinical Trial Summary

The purpose of this study is to test a novel diagnostic immunoassay of platelet function and compare it to the current gold standard platelet function assay by testing the response to aspirin and clopidogrel in a group of healthy volunteers and severely obese individuals and comparing the accuracy of the two tests. The secondary goals will be to evaluate the pharmacodynamic parameters of the antiplatelet agents across the two testing modalities and refine the cutoffs used for the novel assay.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

  • Healthy
  • Platelet Activation Testing Before/After Anti-platelet Therapy
Clinical Trial Details
NCT number NCT04822363
Study type Interventional
Source Beth Israel Deaconess Medical Center
Contact Jeffrey Zwicker, MD
Phone 617-667-9920
Email jzwicker@bidmc.harvard.edu
Status Recruiting
Phase Early Phase 1
Start date August 20, 2021
Completion date April 2025
View Details
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