Healthy Clinical Trial
Official title:
Neuropsychiatric Evaluation of Normal Subjects and Psychiatric and Neurologic Contrast Groups
The purpose of this study is to evaluate the cognitive processes of participants with
schizophrenia, participants with nervous system and mental disorders, and healthy
volunteers.
Participants in this study will undergo cognitive tests of attention, memory, attention.
Participants with attention deficit hyperactivity disorder (ADHD), traumatic brain injury
(TBI), bipolar disorder, and Alzheimer's disease (AD) will be compared with participants
with schizophrenia. A group of healthy adults and children will undergo cognitive tests to
further delineate the degree of impairment in schizophrenia and neurological disorder
participants.
In this study, we propose to administer cognitive tests to schizophrenic patients and to
neurologic patients who will serve as contrast groups for neuropsychological studies of
patients with schizophrenia. These include studies of Alzheimers disease to dissociate size
and organization of lexicon and ADHD to understand error patterns on CPT-type tests of
attention and vigilance. However, the majority of studies will examine schizophrenia in
relation to normal controls.
In addition, we propose to obtain test results from a local sample of normal subjects of
varying ages and educational backgrounds to further delineate degree of impairment in these
clinical groups. As well as assessing adults we wish to assess normal children. In
particular, we wish to identify in children the size of their lexicon and their degree of
semantic organization within their lexicon.
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